TY - JOUR
T1 - Factors involved in the decision to decline prenatal screening with noninvasive prenatal testing (NIPT)
AU - van Prooyen Schuurman, Lisanne
AU - van der Meij, Karuna
AU - van Ravesteyn, Nicolien
AU - Crombag, Neeltje
AU - Gitsels-van der Wal, Janneke
AU - Kooij, Caroline
AU - Martin, Linda
AU - Peters, Ingrid
AU - Polak, Marike
AU - van Vliet-Lachotzki, Elsbeth
AU - Galjaard, Robert-Jan
AU - Henneman, Lidewij
N1 - Publisher Copyright:
© 2022 The Authors. Prenatal Diagnosis published by John Wiley & Sons Ltd.
PY - 2023/4
Y1 - 2023/4
N2 - OBJECTIVE: To investigate factors involved in the decision to decline prenatal screening with noninvasive prenatal testing (NIPT).METHOD: A questionnaire study was conducted among 219 pregnant women in the Netherlands who had declined prenatal screening with NIPT (TRIDENT-2 study). Respondents were selectively recruited from three hospitals and 19 midwifery practices, primarily located in or near socioeconomically disadvantaged neighborhoods. 44.3% of the respondents were of non-Western ethnic origin and 64.4% were religious.RESULTS: Most respondents (77.2%) found the decision to decline NIPT easy to make, and 59.8% had already made the decision before information about NIPT was offered. These respondents were more often religious, multigravida, and had adequate health literacy. The main reasons to decline NIPT were "I would never terminate my pregnancy" (57.1%) and "every child is welcome" (56.2%). For 16.9% of respondents, the out-of-pocket costs (175 euros) played a role in the decision, and the women in this group were more often nonreligious, primigravida, and had inadequate health literacy.CONCLUSION: The primary factors involved in the decision to decline NIPT were related to personal values and beliefs, consistent with autonomous choice. Out-of-pocket costs of NIPT hinder equal access for some pregnant women.
AB - OBJECTIVE: To investigate factors involved in the decision to decline prenatal screening with noninvasive prenatal testing (NIPT).METHOD: A questionnaire study was conducted among 219 pregnant women in the Netherlands who had declined prenatal screening with NIPT (TRIDENT-2 study). Respondents were selectively recruited from three hospitals and 19 midwifery practices, primarily located in or near socioeconomically disadvantaged neighborhoods. 44.3% of the respondents were of non-Western ethnic origin and 64.4% were religious.RESULTS: Most respondents (77.2%) found the decision to decline NIPT easy to make, and 59.8% had already made the decision before information about NIPT was offered. These respondents were more often religious, multigravida, and had adequate health literacy. The main reasons to decline NIPT were "I would never terminate my pregnancy" (57.1%) and "every child is welcome" (56.2%). For 16.9% of respondents, the out-of-pocket costs (175 euros) played a role in the decision, and the women in this group were more often nonreligious, primigravida, and had inadequate health literacy.CONCLUSION: The primary factors involved in the decision to decline NIPT were related to personal values and beliefs, consistent with autonomous choice. Out-of-pocket costs of NIPT hinder equal access for some pregnant women.
KW - Costs and Cost Analysis
KW - Down Syndrome/diagnosis
KW - Female
KW - Humans
KW - Infant, Newborn
KW - Netherlands
KW - Noninvasive Prenatal Testing
KW - Pregnancy
KW - Prenatal Diagnosis
UR - http://www.scopus.com/inward/record.url?scp=85138701625&partnerID=8YFLogxK
U2 - 10.1002/pd.6242
DO - 10.1002/pd.6242
M3 - Article
C2 - 36109868
SN - 0197-3851
VL - 43
SP - 467
EP - 476
JO - Prenatal Diagnosis
JF - Prenatal Diagnosis
IS - 4
ER -