Extending the quasi-steady state approximation by changing variables

José A.M. Borghans; Rob J. De Boer; Lee A. Segel

doi:10.1007/BF02458281

Extending the quasi-steady state approximation by changing variables

José A.M. Borghans^*
, Rob J. De Boer
, Lee A. Segel

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

192 Citations (Scopus)

Abstract

The parameter domain for which the quasi-steady state assumption is valid can be considerably extended merely by a simple change of variable. This is demonstrated for a variety of biologically significant examples taken from enzyme kinetics, immunology and ecology.

Original language	English
Pages (from-to)	43-63
Number of pages	21
Journal	Bulletin of Mathematical Biology
Volume	58
Issue number	1
DOIs	https://doi.org/10.1007/BF02458281
Publication status	Published - 1996
Externally published	Yes

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title = "Extending the quasi-steady state approximation by changing variables",

abstract = "The parameter domain for which the quasi-steady state assumption is valid can be considerably extended merely by a simple change of variable. This is demonstrated for a variety of biologically significant examples taken from enzyme kinetics, immunology and ecology.",

author = "Borghans, \{Jos{\'e} A.M.\} and \{De Boer\}, \{Rob J.\} and Segel, \{Lee A.\}",

note = "Funding Information: We thank the non-linear systems (NLS) program of the Netherlands Organization for Scientific Research (NWO) for support of the visit of LAS to Utrecht. LAS acknowledges partial support by the U.S.-Israel Binational Science Foundation (Grant 92-00171).",

year = "1996",

doi = "10.1007/BF02458281",

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volume = "58",

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journal = "Bulletin of Mathematical Biology",

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T1 - Extending the quasi-steady state approximation by changing variables

AU - Borghans, José A.M.

AU - De Boer, Rob J.

AU - Segel, Lee A.

N1 - Funding Information: We thank the non-linear systems (NLS) program of the Netherlands Organization for Scientific Research (NWO) for support of the visit of LAS to Utrecht. LAS acknowledges partial support by the U.S.-Israel Binational Science Foundation (Grant 92-00171).

PY - 1996

Y1 - 1996

N2 - The parameter domain for which the quasi-steady state assumption is valid can be considerably extended merely by a simple change of variable. This is demonstrated for a variety of biologically significant examples taken from enzyme kinetics, immunology and ecology.

AB - The parameter domain for which the quasi-steady state assumption is valid can be considerably extended merely by a simple change of variable. This is demonstrated for a variety of biologically significant examples taken from enzyme kinetics, immunology and ecology.

UR - https://www.scopus.com/pages/publications/0029681614

U2 - 10.1007/BF02458281

DO - 10.1007/BF02458281

M3 - Article

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AN - SCOPUS:0029681614

SN - 0092-8240

VL - 58

SP - 43

EP - 63

JO - Bulletin of Mathematical Biology

JF - Bulletin of Mathematical Biology

IS - 1

ER -

Extending the quasi-steady state approximation by changing variables

Abstract

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