TY - JOUR
T1 - Exploring lifelong overactive bladder
T2 - Transitions, evidence, and clinical implications; A modified Delphi process
AU - Bou Kheir, George
AU - Verbakel, Irina
AU - Vande Walle, Johan
AU - Wyndaele, Michel
AU - Sinha, Sanjay
AU - Arlandis, Salvador
AU - Raes, Ann
AU - Abrams, Paul
AU - Wein, Alan
AU - Hervé, François
AU - Everaert, Karel
N1 - Publisher Copyright:
© 2023 Wiley Periodicals LLC.
PY - 2024/6
Y1 - 2024/6
N2 - INTRODUCTION: Overactive bladder (OAB) is a prevalent urological condition characterized by urinary urgency, with or without urgency urinary incontinence, accompanied by increased daytime frequency and nocturia. However, the current definition of OAB lacks a specified time frame, hindering our understanding of the temporal aspects and transitions that occur within the OAB spectrum.METHODS: A modified Delphi study was conducted in three rounds, involving a panel of international experts in functional urology, urogynaecology, geriatrics, transitional medicine, and pediatric urology. The study took place between February 2023 and June 2023 and employed two sequential rounds of online surveys, followed by a final hybrid group discussion session in June 2023.RESULTS: The Delphi process resulted in a consensus definition of lifelong OAB as a persistent and continuous condition that may manifest differently from birth and evolve over time, with varying levels of clinical perception. The course of its progression is influenced by transition periods and modifying factors, mainly anatomical, hormonal, and psychosocial/stressors. Three main transition periods were identified: achievement of daytime continence, adulthood to elderly, and transition to frail elderly. The panel also considered the therapeutic and diagnostic implications of lifelong OAB, as well as future research prospects in terms of importance and feasibility.CONCLUSIONS: Future longitudinal research is needed to develop this concept and further identify transitions and temporal dynamics.
AB - INTRODUCTION: Overactive bladder (OAB) is a prevalent urological condition characterized by urinary urgency, with or without urgency urinary incontinence, accompanied by increased daytime frequency and nocturia. However, the current definition of OAB lacks a specified time frame, hindering our understanding of the temporal aspects and transitions that occur within the OAB spectrum.METHODS: A modified Delphi study was conducted in three rounds, involving a panel of international experts in functional urology, urogynaecology, geriatrics, transitional medicine, and pediatric urology. The study took place between February 2023 and June 2023 and employed two sequential rounds of online surveys, followed by a final hybrid group discussion session in June 2023.RESULTS: The Delphi process resulted in a consensus definition of lifelong OAB as a persistent and continuous condition that may manifest differently from birth and evolve over time, with varying levels of clinical perception. The course of its progression is influenced by transition periods and modifying factors, mainly anatomical, hormonal, and psychosocial/stressors. Three main transition periods were identified: achievement of daytime continence, adulthood to elderly, and transition to frail elderly. The panel also considered the therapeutic and diagnostic implications of lifelong OAB, as well as future research prospects in terms of importance and feasibility.CONCLUSIONS: Future longitudinal research is needed to develop this concept and further identify transitions and temporal dynamics.
KW - lifelong
KW - modified Delphi process
KW - overactive bladder
KW - transition phases
KW - transitional care
UR - http://www.scopus.com/inward/record.url?scp=85183862689&partnerID=8YFLogxK
U2 - 10.1002/nau.25307
DO - 10.1002/nau.25307
M3 - Review article
C2 - 38289322
SN - 0733-2467
VL - 43
SP - 1040
EP - 1057
JO - Neurourology and Urodynamics
JF - Neurourology and Urodynamics
IS - 5
ER -