Expanding the Tissue Toolbox: Deriving Colon Tissue from Human Pluripotent Stem Cells

Lotte Bruens; Hugo J.G. Snippert

doi:10.1016/j.stem.2017.06.001

Expanding the Tissue Toolbox: Deriving Colon Tissue from Human Pluripotent Stem Cells

Lotte Bruens, Hugo J.G. Snippert^*

^*Corresponding author for this work

Research output: Contribution to journal › Short survey › peer-review

Abstract

Organoid technology holds great potential for disease modeling and regenerative medicine. In this issue of Cell Stem Cell, Múnera et al. (2017) establish the generation of pluripotent stem cell-derived colon organoids that upon transplantation in mice, resembling human colon to a large extent, opening up avenues to study disease pathogenesis in human colon tissue. Organoid technology holds great potential for disease modeling and regenerative medicine. In this issue of Cell Stem Cell, Múnera et al. (2017) establish the generation of pluripotent stem cell-derived colon organoids that upon transplantation in mice, strikingly resemble human colon, opening up avenues to study disease pathogenesis in human colon tissue.

Original language	English
Pages (from-to)	3-5
Number of pages	3
Journal	Cell Stem Cell
Volume	21
Issue number	1
DOIs	https://doi.org/10.1016/j.stem.2017.06.001
Publication status	Published - 6 Jul 2017

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title = "Expanding the Tissue Toolbox: Deriving Colon Tissue from Human Pluripotent Stem Cells",

abstract = "Organoid technology holds great potential for disease modeling and regenerative medicine. In this issue of Cell Stem Cell, M{\'u}nera et al. (2017) establish the generation of pluripotent stem cell-derived colon organoids that upon transplantation in mice, resembling human colon to a large extent, opening up avenues to study disease pathogenesis in human colon tissue. Organoid technology holds great potential for disease modeling and regenerative medicine. In this issue of Cell Stem Cell, M{\'u}nera et al. (2017) establish the generation of pluripotent stem cell-derived colon organoids that upon transplantation in mice, strikingly resemble human colon, opening up avenues to study disease pathogenesis in human colon tissue.",

author = "Lotte Bruens and Snippert, {Hugo J.G.}",

year = "2017",

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doi = "10.1016/j.stem.2017.06.001",

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T2 - Deriving Colon Tissue from Human Pluripotent Stem Cells

AU - Bruens, Lotte

AU - Snippert, Hugo J.G.

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Y1 - 2017/7/6

N2 - Organoid technology holds great potential for disease modeling and regenerative medicine. In this issue of Cell Stem Cell, Múnera et al. (2017) establish the generation of pluripotent stem cell-derived colon organoids that upon transplantation in mice, resembling human colon to a large extent, opening up avenues to study disease pathogenesis in human colon tissue. Organoid technology holds great potential for disease modeling and regenerative medicine. In this issue of Cell Stem Cell, Múnera et al. (2017) establish the generation of pluripotent stem cell-derived colon organoids that upon transplantation in mice, strikingly resemble human colon, opening up avenues to study disease pathogenesis in human colon tissue.

AB - Organoid technology holds great potential for disease modeling and regenerative medicine. In this issue of Cell Stem Cell, Múnera et al. (2017) establish the generation of pluripotent stem cell-derived colon organoids that upon transplantation in mice, resembling human colon to a large extent, opening up avenues to study disease pathogenesis in human colon tissue. Organoid technology holds great potential for disease modeling and regenerative medicine. In this issue of Cell Stem Cell, Múnera et al. (2017) establish the generation of pluripotent stem cell-derived colon organoids that upon transplantation in mice, strikingly resemble human colon, opening up avenues to study disease pathogenesis in human colon tissue.

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M3 - Short survey

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JF - Cell Stem Cell

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Expanding the Tissue Toolbox: Deriving Colon Tissue from Human Pluripotent Stem Cells

Abstract

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