Exercise stress testing in children with metabolic or neuromuscular disorders

Tim Takken; Wim G Groen; Erik H Hulzebos; Cornelia G Ernsting; Peter M van Hasselt; Berthil H Prinsen; Paul J Helders; Gepke Visser

doi:10.1155/2010/254829

Exercise stress testing in children with metabolic or neuromuscular disorders

Tim Takken, Wim G Groen, Erik H Hulzebos, Cornelia G Ernsting, Peter M van Hasselt, Berthil H Prinsen, Paul J Helders, Gepke Visser

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

The role of exercise as a diagnostic or therapeutic tool in patients with a metabolic disease (MD) or neuromuscular disorder (NMD) is relatively underresearched. In this paper we describe the metabolic profiles during exercise in 13 children (9 boys, 4 girls, age 5-15 yrs) with a diagnosed MD or NMD. Graded cardiopulmonary exercise tests and/or a 90-min prolonged submaximal exercise test were performed. During exercise, respiratory gas-exchange and heart rate were monitored; blood and urine samples were collected for biochemical analysis at set time points. Several characteristics in our patient group were observed, which reflected the differences in pathophysiology of the various disorders. Metabolic profiles during exercises CPET and PXT seem helpful in the evaluation of patients with a MD or NMD.

Original language	English
Journal	International Journal of Pediatrics
Volume	2010
DOIs	https://doi.org/10.1155/2010/254829
Publication status	Published - 2010

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10.1155/2010/254829

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title = "Exercise stress testing in children with metabolic or neuromuscular disorders",

abstract = "The role of exercise as a diagnostic or therapeutic tool in patients with a metabolic disease (MD) or neuromuscular disorder (NMD) is relatively underresearched. In this paper we describe the metabolic profiles during exercise in 13 children (9 boys, 4 girls, age 5-15 yrs) with a diagnosed MD or NMD. Graded cardiopulmonary exercise tests and/or a 90-min prolonged submaximal exercise test were performed. During exercise, respiratory gas-exchange and heart rate were monitored; blood and urine samples were collected for biochemical analysis at set time points. Several characteristics in our patient group were observed, which reflected the differences in pathophysiology of the various disorders. Metabolic profiles during exercises CPET and PXT seem helpful in the evaluation of patients with a MD or NMD.",

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year = "2010",

doi = "10.1155/2010/254829",

language = "English",

volume = "2010",

journal = "International Journal of Pediatrics",

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T1 - Exercise stress testing in children with metabolic or neuromuscular disorders

AU - Takken, Tim

AU - Groen, Wim G

AU - Hulzebos, Erik H

AU - Ernsting, Cornelia G

AU - van Hasselt, Peter M

AU - Prinsen, Berthil H

AU - Helders, Paul J

AU - Visser, Gepke

PY - 2010

Y1 - 2010

N2 - The role of exercise as a diagnostic or therapeutic tool in patients with a metabolic disease (MD) or neuromuscular disorder (NMD) is relatively underresearched. In this paper we describe the metabolic profiles during exercise in 13 children (9 boys, 4 girls, age 5-15 yrs) with a diagnosed MD or NMD. Graded cardiopulmonary exercise tests and/or a 90-min prolonged submaximal exercise test were performed. During exercise, respiratory gas-exchange and heart rate were monitored; blood and urine samples were collected for biochemical analysis at set time points. Several characteristics in our patient group were observed, which reflected the differences in pathophysiology of the various disorders. Metabolic profiles during exercises CPET and PXT seem helpful in the evaluation of patients with a MD or NMD.

AB - The role of exercise as a diagnostic or therapeutic tool in patients with a metabolic disease (MD) or neuromuscular disorder (NMD) is relatively underresearched. In this paper we describe the metabolic profiles during exercise in 13 children (9 boys, 4 girls, age 5-15 yrs) with a diagnosed MD or NMD. Graded cardiopulmonary exercise tests and/or a 90-min prolonged submaximal exercise test were performed. During exercise, respiratory gas-exchange and heart rate were monitored; blood and urine samples were collected for biochemical analysis at set time points. Several characteristics in our patient group were observed, which reflected the differences in pathophysiology of the various disorders. Metabolic profiles during exercises CPET and PXT seem helpful in the evaluation of patients with a MD or NMD.

U2 - 10.1155/2010/254829

DO - 10.1155/2010/254829

M3 - Article

C2 - 20706686

SN - 1687-9740

VL - 2010

JO - International Journal of Pediatrics

JF - International Journal of Pediatrics

ER -

Exercise stress testing in children with metabolic or neuromuscular disorders

Abstract

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