Everything has its time: Id2 clocks embryonic specification of Lgr5+ gut stem cells

Kai Kretzschmar; Hans Clevers

doi:10.15252/embj.201796482

Everything has its time: Id2 clocks embryonic specification of Lgr5⁺ gut stem cells

Kai Kretzschmar, Hans Clevers

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

While adult intestinal stem cells and their niche are well characterised, their developmental specification is still poorly understood. In this issue of The EMBO Journal, Nigmatullina et al (2017) show that maturation of Lgr5⁺ progenitors in the small intestinal epithelium during murine embryonic development is controlled by the transcription factor Id2.

Original language	English
Pages (from-to)	837-839
Number of pages	3
Journal	EMBO Journal
Volume	36
Issue number	7
DOIs	https://doi.org/10.15252/embj.201796482
Publication status	Published - 3 Apr 2017

Keywords

Cell Differentiation
Humans
Receptors, G-Protein-Coupled
Stem Cells
Journal Article
Comment

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10.15252/embj.201796482

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abstract = "While adult intestinal stem cells and their niche are well characterised, their developmental specification is still poorly understood. In this issue of The EMBO Journal, Nigmatullina et al (2017) show that maturation of Lgr5+ progenitors in the small intestinal epithelium during murine embryonic development is controlled by the transcription factor Id2.",

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Everything has its time: Id2 clocks embryonic specification of Lgr5⁺ gut stem cells

Abstract

Keywords

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