Evaluation of Online Plan Adaptation Strategies for the 1.5T MR-linac Based on "First-In-Man" Treatments

Dennis Winkel; Gijsbert H Bol; Ilse H Kiekebosch; Bram Van Asselen; Petra S Kroon; Ina M Jürgenliemk-Schulz; Bas W Raaymakers

doi:10.7759/cureus.2431

Evaluation of Online Plan Adaptation Strategies for the 1.5T MR-linac Based on "First-In-Man" Treatments

Dennis Winkel, Gijsbert H Bol, Ilse H Kiekebosch, Bram Van Asselen, Petra S Kroon, Ina M Jürgenliemk-Schulz, Bas W Raaymakers

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

The superior soft tissue contrast provided by magnetic resonance (MR) images on the 1.5T MR-linac allows for the incorporation of patient anatomy information. In this retrospective case study, we present the simulated dosimetric effects and timings of full online replanning as compared to the five plan adaptation methods currently available on the 1.5T MR-linac treatment system. For this case, it is possible to create treatment plans with all six methods within a time slot suitable for an online treatment procedure. However, large dosimetric differences between the plan adaptation methods and full online replanning are present with regards to target coverage and dose to organs at risk (OARs).

Original language	English
Article number	e2431
Journal	Cureus
Volume	10
Issue number	4
DOIs	https://doi.org/10.7759/cureus.2431
Publication status	Published - 5 Apr 2018

Keywords

mr-linac
adaptive planning
adaptive radiotherapy
online replanning
lumbar spine bonemetastases
mr-guided-rt
mr-igrt
mr guided radiotherapy

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abstract = "The superior soft tissue contrast provided by magnetic resonance (MR) images on the 1.5T MR-linac allows for the incorporation of patient anatomy information. In this retrospective case study, we present the simulated dosimetric effects and timings of full online replanning as compared to the five plan adaptation methods currently available on the 1.5T MR-linac treatment system. For this case, it is possible to create treatment plans with all six methods within a time slot suitable for an online treatment procedure. However, large dosimetric differences between the plan adaptation methods and full online replanning are present with regards to target coverage and dose to organs at risk (OARs).",

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AU - Winkel, Dennis

AU - Bol, Gijsbert H

AU - Kiekebosch, Ilse H

AU - Van Asselen, Bram

AU - Kroon, Petra S

AU - Jürgenliemk-Schulz, Ina M

AU - Raaymakers, Bas W

PY - 2018/4/5

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AB - The superior soft tissue contrast provided by magnetic resonance (MR) images on the 1.5T MR-linac allows for the incorporation of patient anatomy information. In this retrospective case study, we present the simulated dosimetric effects and timings of full online replanning as compared to the five plan adaptation methods currently available on the 1.5T MR-linac treatment system. For this case, it is possible to create treatment plans with all six methods within a time slot suitable for an online treatment procedure. However, large dosimetric differences between the plan adaptation methods and full online replanning are present with regards to target coverage and dose to organs at risk (OARs).

KW - mr-linac

KW - adaptive planning

KW - adaptive radiotherapy

KW - online replanning

KW - lumbar spine bonemetastases

KW - mr-guided-rt

KW - mr-igrt

KW - mr guided radiotherapy

U2 - 10.7759/cureus.2431

DO - 10.7759/cureus.2431

M3 - Article

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JO - Cureus

JF - Cureus

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M1 - e2431

ER -

Evaluation of Online Plan Adaptation Strategies for the 1.5T MR-linac Based on "First-In-Man" Treatments

Abstract

Keywords

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