Ethical challenges for pediatric liver organoid transplantation

Sarah A Schneemann; Sarah N Boers; Johannes J M van Delden; Edward E S Nieuwenhuis; Sabine A Fuchs; Annelien L Bredenoord

doi:10.1126/scitranslmed.aau8471

Ethical challenges for pediatric liver organoid transplantation

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Abstract

Liver organoid transplantation may be a less invasive alternative to liver transplant, but is it ethically acceptable to include children with liver disease in a first-in-human clinical trial of this new intervention?

Original language	English
Article number	eaau8471
Pages (from-to)	1-3
Journal	Science translational medicine
Volume	12
Issue number	552
DOIs	https://doi.org/10.1126/scitranslmed.aau8471
Publication status	Published - 15 Jul 2020

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10.1126/scitranslmed.aau8471

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title = "Ethical challenges for pediatric liver organoid transplantation",

abstract = "Liver organoid transplantation may be a less invasive alternative to liver transplant, but is it ethically acceptable to include children with liver disease in a first-in-human clinical trial of this new intervention?",

author = "Schneemann, \{Sarah A\} and Boers, \{Sarah N\} and \{van Delden\}, \{Johannes J M\} and Nieuwenhuis, \{Edward E S\} and Fuchs, \{Sabine A\} and Bredenoord, \{Annelien L\}",

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AU - Schneemann, Sarah A

AU - Boers, Sarah N

AU - van Delden, Johannes J M

AU - Nieuwenhuis, Edward E S

AU - Fuchs, Sabine A

AU - Bredenoord, Annelien L

N1 - Publisher Copyright: Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Copyright: This record is sourced from MEDLINE/PubMed, a database of the U.S. National Library of Medicine

PY - 2020/7/15

Y1 - 2020/7/15

N2 - Liver organoid transplantation may be a less invasive alternative to liver transplant, but is it ethically acceptable to include children with liver disease in a first-in-human clinical trial of this new intervention?

AB - Liver organoid transplantation may be a less invasive alternative to liver transplant, but is it ethically acceptable to include children with liver disease in a first-in-human clinical trial of this new intervention?

UR - https://www.scopus.com/pages/publications/85088157344

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JO - Science translational medicine

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Ethical challenges for pediatric liver organoid transplantation

Abstract

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