Ervaringen met MRI-geleide brachytherapie bij prostaatkankerrecidief

Marnix J.A. Rasing; Max Peters; M. A. Moerland; Juus L. Noteboom; Jan J. Lagendijk; Jochem R.N. van der Voort van Zyp

Ervaringen met MRI-geleide brachytherapie bij prostaatkankerrecidief

Translated title of the contribution: Experiences with MRI-guided brachytherapy for radiorecurrent prostate cancer

Marnix J.A. Rasing, Max Peters, M. A. Moerland, Juus L. Noteboom, Jan J. Lagendijk, Jochem R.N. van der Voort van Zyp

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

MR-guided brachytherapy offers a focal salvage treatment for the local recurrence in case of isolated locally recurrent prostate cancer in the prostate and/or seminal vesicles after primary radiotherapy. By focusing on only the local recurrence instead of the whole prostate, chances of additional toxicity of the bladder, urethra and rectum can be minimized. In almost all patients, the treatment leads to a good initial treatment response that persists in about half of patients, while others will develop progressive disease later on. For selecting suitable patients, factors such as preexistent urinary- and bowel complaints, localization and size of the recurrence, PSA doubling time and time between primary radiotherapy and development of the recurrence are relevant. MR-guided brachytherapy can provide a suitable salvage strategy, with the aims of deferring androgen deprivation therapy and a chance of cure.

Translated title of the contribution	Experiences with MRI-guided brachytherapy for radiorecurrent prostate cancer
Original language	Dutch
Article number	d6966
Journal	Nederlands Tijdschrift voor Geneeskunde
Volume	166
Publication status	Published - 5 Oct 2022

Keywords

Male
Humans
Brachytherapy
Prostatic Neoplasms/radiotherapy
Prostate-Specific Antigen
Androgen Antagonists
Androgens
Neoplasm Recurrence, Local/radiotherapy
Magnetic Resonance Imaging

Cite this

@article{552e337fc00643478ead940ac5abfbe6,

title = "Ervaringen met MRI-geleide brachytherapie bij prostaatkankerrecidief",

abstract = "MR-guided brachytherapy offers a focal salvage treatment for the local recurrence in case of isolated locally recurrent prostate cancer in the prostate and/or seminal vesicles after primary radiotherapy. By focusing on only the local recurrence instead of the whole prostate, chances of additional toxicity of the bladder, urethra and rectum can be minimized. In almost all patients, the treatment leads to a good initial treatment response that persists in about half of patients, while others will develop progressive disease later on. For selecting suitable patients, factors such as preexistent urinary- and bowel complaints, localization and size of the recurrence, PSA doubling time and time between primary radiotherapy and development of the recurrence are relevant. MR-guided brachytherapy can provide a suitable salvage strategy, with the aims of deferring androgen deprivation therapy and a chance of cure.",

keywords = "Male, Humans, Brachytherapy, Prostatic Neoplasms/radiotherapy, Prostate-Specific Antigen, Androgen Antagonists, Androgens, Neoplasm Recurrence, Local/radiotherapy, Magnetic Resonance Imaging",

author = "Rasing, {Marnix J.A.} and Max Peters and Moerland, {M. A.} and Noteboom, {Juus L.} and Lagendijk, {Jan J.} and {van der Voort van Zyp}, {Jochem R.N.}",

year = "2022",

month = oct,

day = "5",

language = "Dutch",

volume = "166",

journal = "Nederlands Tijdschrift voor Geneeskunde",

issn = "0028-2162",

publisher = "Bohn Stafleu van Loghum",

}

TY - JOUR

T1 - Ervaringen met MRI-geleide brachytherapie bij prostaatkankerrecidief

AU - Rasing, Marnix J.A.

AU - Peters, Max

AU - Moerland, M. A.

AU - Noteboom, Juus L.

AU - Lagendijk, Jan J.

AU - van der Voort van Zyp, Jochem R.N.

PY - 2022/10/5

Y1 - 2022/10/5

N2 - MR-guided brachytherapy offers a focal salvage treatment for the local recurrence in case of isolated locally recurrent prostate cancer in the prostate and/or seminal vesicles after primary radiotherapy. By focusing on only the local recurrence instead of the whole prostate, chances of additional toxicity of the bladder, urethra and rectum can be minimized. In almost all patients, the treatment leads to a good initial treatment response that persists in about half of patients, while others will develop progressive disease later on. For selecting suitable patients, factors such as preexistent urinary- and bowel complaints, localization and size of the recurrence, PSA doubling time and time between primary radiotherapy and development of the recurrence are relevant. MR-guided brachytherapy can provide a suitable salvage strategy, with the aims of deferring androgen deprivation therapy and a chance of cure.

AB - MR-guided brachytherapy offers a focal salvage treatment for the local recurrence in case of isolated locally recurrent prostate cancer in the prostate and/or seminal vesicles after primary radiotherapy. By focusing on only the local recurrence instead of the whole prostate, chances of additional toxicity of the bladder, urethra and rectum can be minimized. In almost all patients, the treatment leads to a good initial treatment response that persists in about half of patients, while others will develop progressive disease later on. For selecting suitable patients, factors such as preexistent urinary- and bowel complaints, localization and size of the recurrence, PSA doubling time and time between primary radiotherapy and development of the recurrence are relevant. MR-guided brachytherapy can provide a suitable salvage strategy, with the aims of deferring androgen deprivation therapy and a chance of cure.

KW - Male

KW - Humans

KW - Brachytherapy

KW - Prostatic Neoplasms/radiotherapy

KW - Prostate-Specific Antigen

KW - Androgen Antagonists

KW - Androgens

KW - Neoplasm Recurrence, Local/radiotherapy

KW - Magnetic Resonance Imaging

UR - http://www.scopus.com/inward/record.url?scp=85140932859&partnerID=8YFLogxK

M3 - Article

C2 - 36300470

AN - SCOPUS:85140932859

SN - 0028-2162

VL - 166

JO - Nederlands Tijdschrift voor Geneeskunde

JF - Nederlands Tijdschrift voor Geneeskunde

M1 - d6966

ER -

Ervaringen met MRI-geleide brachytherapie bij prostaatkankerrecidief

Abstract

Keywords

Other files and links

Fingerprint

Cite this