Abstract
(Cancer Cell 33, 922–936.e1–e10; May 14, 2018) We reported the generation of a bispecific antibody against HER2 and HER3 using an unbiased combinatorial screening approach. During the preparation of the manuscript, we unintentionally introduced an error in Figure 2C and its legend, where a treatment arm was incorrectly labeled as “MM-121” and should have been “PG3178.” We have now corrected Figure 2 and its corresponding legend, shown here. In the Results section, when describing the results presented in Figure 2C, “PG3178” was again incorrectly referenced as “MM-121”. The corrected text reads as follows: “As previously reported for the tyrosine kinase inhibitor lapatinib (Wilson et al., 2012), the inhibitory activity of HER3 mAb PG3178 (2 nM, Figure 2C) was reduced in a dose-dependent manner as the HRG concentration increased beyond its EC90 value for growth stimulation (0.11 nM)”. The other references to the analog of MM-121 in the manuscript are correct. We apologize for any confusions this error may have caused.[Figure
| Original language | English |
|---|---|
| Pages (from-to) | 1163-1164 |
| Number of pages | 2 |
| Journal | Cancer Cell |
| Volume | 39 |
| Issue number | 8 |
| DOIs |
|
| Publication status | Published - 9 Aug 2021 |
| Externally published | Yes |
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Dive into the research topics of 'Erratum: Unbiased Combinatorial Screening Identifies a Bispecific IgG1 that Potently Inhibits HER3 Signaling via HER2-Guided Ligand Blockade (Cancer Cell (2018) 33(5) (922–936.e10), (S1535610818301740), (10.1016/j.ccell.2018.04.003))'. Together they form a unique fingerprint.Research output
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Unbiased Combinatorial Screening Identifies a Bispecific IgG1 that Potently Inhibits HER3 Signaling via HER2-Guided Ligand Blockade
Geuijen, C. A. W., De Nardis, C., Maussang, D., Rovers, E., Gallenne, T., Hendriks, L. J. A., Visser, T., Nijhuis, R., Logtenberg, T., de Kruif, J., Gros, P. & Throsby, M., 14 May 2018, In: Cancer Cell. 33, 5, p. 922-936.e10Research output: Contribution to journal › Article › Academic › peer-review
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