Abstract
Aneuploidy is one of the most prevalent phenotypes of human tumours, but the underlying cause of this phenomenon remains highly debated. Entosis, the invasion of a living cell into another cell's cytoplasm, is now shown to perturb cytokinesis and induce the formation of aneuploid cells.
| Original language | English |
|---|---|
| Pages (from-to) | 199-201 |
| Number of pages | 3 |
| Journal | Nature Cell Biology |
| Volume | 13 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - Mar 2011 |
Keywords
- Aneuploidy
- Animals
- Cell Death
- Centrosome/ultrastructure
- Cytokinesis
- Cytoplasm/metabolism
- Female
- Humans
- Male
- Mitosis
- Models, Biological
- Neoplasms/pathology
- Phosphorylation
- Spermatozoa/pathology
- Spindle Apparatus