Abstract
We assessed the effects of two doses of a water-soluble preparation of acetylsalicylic acid, or aspirin (30 mg vs. 283 mg a day), on the occurrence af death from all vascular causes, nonfatal stroke, or nonfatal myocardial infarction in a double-blind, randomized, controlled clinical trial in patients who had had a transient ischemic attack or minor stroke. A total of 3131 patients participated in the study. The mean follow-up was 2.6 years. Our data indicate that 30 mg of aspirin daily is no less effective in the prevention of vascular events than a 283-mg dose in patients with a transient ischemic attack or minor stroke, and has fewer adverse effects. The differences between TIAs, RINDs and minor strokes are quantitative rather than qualitative. The three groups should be regarded as a continuum.
| Translated title of the contribution | Some results of the Dutch TIA trial |
|---|---|
| Original language | Dutch |
| Pages (from-to) | 171-176+183 |
| Journal | TGO - Tijdschrift voor Therapie Geneesmiddel en Onderzoek |
| Volume | 17 |
| Issue number | 6 |
| Publication status | Published - 1992 |