Emergence of rifampin-resistant Streptococcus pneumoniae as a result of antimicrobial therapy for penicillin-resistant strains

Peter M.B. Van Tilburg, Debby Bogaert, Marcel Sluijter, Arjan R. Jansz, Ronald De Groot, Peter W.M. Hermans

Research output: Contribution to journalArticleAcademicpeer-review

10 Citations (Scopus)

Abstract

A multidrug-resistant strain of Streptococcus pneumoniae was isolated in The Netherlands during a nosocomial outbreak among 36 patients who mainly had chronic obstructive pulmonary disease. After the commencement of barrier nursing and short-term ceftriaxone-rifampin eradication therapy, the epidemic ceased. However, eradication therapy failed in 3 patients, and follow-up investigation of these patients showed the emergence of rifampin-resistant isolates.

Original languageEnglish
Pages (from-to)e93-96
JournalClinical infectious diseases: an official publication of the Infectious Diseases Society of America
Volume33
Issue number8
DOIs
Publication statusPublished - 15 Oct 2001
Externally publishedYes

Fingerprint

Dive into the research topics of 'Emergence of rifampin-resistant Streptococcus pneumoniae as a result of antimicrobial therapy for penicillin-resistant strains'. Together they form a unique fingerprint.

Cite this