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Electrophysiological abnormalities in VLCAD deficient hiPSC-cardiomyocytes can be improved by lowering accumulation of fatty acid oxidation intermediates

  • Suzan J.G. Knottnerus
  • , Isabella Mengarelli
  • , Rob C.I. Wüst
  • , Antonius Baartscheer
  • , Jeannette C. Bleeker
  • , Ruben Coronel
  • , Sacha Ferdinandusse
  • , Kaomei Guan
  • , Lodewijk Ijlst
  • , Wener Li
  • , Xiaojing Luo
  • , Vincent M. Portero
  • , Ying Ulbricht
  • , Gepke Visser
  • , Ronald J.A. Wanders
  • , Frits A. Wijburg
  • , Arie O. Verkerk
  • , Riekelt H. Houtkooper*
  • , Connie R. Bezzina
  • *Corresponding author for this work

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Biochemistry, Genetics and Molecular Biology