Elastic demons: Characterizing cortical development in neonates using an implicit surface registration

Paul C. Pearlman*, Ivana Išgum, Karina J. Kersbergen, Manon J.N.L. Benders, Max A. Viergever, Josien P.W. Pluim

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

1 Citation (Scopus)

Abstract

We present an approach for nonrigid registration of consecutive neonatal cortical surfaces from MR images acquired at 30 and 40 week corrected gestational ages. Surfaces are registered implicitly using a method based on the Demons algorithm. Our key innovation is removing the Gaussian smoothing term in Demons in favor of an elasticity constraint that simultaneously promotes more realistic deformations and smooths the deformation field. This is advantageous because the constraint smooths the deformation field along the surface rather than across it. Therefore, fine deformations, such as those necessary to characterize small, new cortical folds, are preserved. The estimated deformation fields are then used to characterize brain development.

Original languageEnglish
Title of host publicationSpatio-temporal Image Analysis for Longitudinal and Time-Series Image Data - Second International Workshop, STIA 2012, Held in Conjunction with MICCAI 2012, Proceedings
Pages38-49
Number of pages12
DOIs
Publication statusPublished - 30 Oct 2012
Event2nd International Workshop on Spatiotemporal Image Analysis for Longitudinal and Time-Series Image Data, STIA 2012, Held in Conjunction with the International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2012 - Nice, France
Duration: 1 Oct 20121 Oct 2012

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume7570 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference2nd International Workshop on Spatiotemporal Image Analysis for Longitudinal and Time-Series Image Data, STIA 2012, Held in Conjunction with the International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2012
Country/TerritoryFrance
CityNice
Period1/10/121/10/12

Fingerprint

Dive into the research topics of 'Elastic demons: Characterizing cortical development in neonates using an implicit surface registration'. Together they form a unique fingerprint.

Cite this