TY - JOUR
T1 - Effects of sesame, canola and sesame-canola oils on body weight and composition in adults with type 2 diabetes mellitus
T2 - a randomized, triple-blind, cross-over clinical trial
AU - Raeisi-Dehkordi, Hamidreza
AU - Amiri, Mojgan
AU - Moghtaderi, Fatemeh
AU - Zimorovat, Alireza
AU - Rahmanian, Masoud
AU - Mozaffari-Khosravi, Hassan
AU - Salehi-Abargouei, Amin
N1 - Funding Information:
We appreciate the participants for their voluntary involvement in the project. Also, we are thankful to Shahid Sadoughi University of Medical Sciences and Neshatavar food industry company (Datis Corporation) for their joint funding of this study. We thank the research council of Nutrition and Food Security Research Center and diabetes research center of Shahid Sadoughi University of Medical Sciences, Yazd, Iran, for their scientific support and close cooperation, respectively. The trial has been registered in the Iranian registry of clinical trials as IRCT2016091312571N6 ( http://en.irct.ir/trial/12622 ). The current study was funded by Shahid Sadoughi University of Medical Sciences ( http://www.ssu.ac.ir ) and Neshatavar food industry (Datis Corporation; http://www.neshatavar.com/?l=EN ). Datis Corporation also provided all of the treatment oils consumed during the study, including canola, sesame, sesame‐canola and sunflower oils. Datis Corporation had no role in the design and conduct of this manuscript; collection, management, analysis and interpretation of the data; and preparation of this manuscript.
Funding Information:
The study was jointly funded by Shahid Sadoughi University of Medical sciences and Datis Corporation. The investigators declared that they did not have a direct financial relationship with Datis Corporation and Shahid Sadoughi University of Medical Sciences received the funds and delivered them to the investigators. Datis Corporation did not take any part in the conception, design, the execution of the study protocol, and the reporting of the study results. The corporation did not have any other relationship with the investigators. The authors declare that they have no other potential personal or financial conflicts of interest. The principal investigator (ASA) declares that he has full access to the data and samples provided by this project.
Funding Information:
We appreciate the participants for their voluntary involvement in the project. Also, we are thankful to Shahid Sadoughi University of Medical Sciences and Neshatavar food industry company (Datis Corporation) for their joint funding of this study. We thank the research council of Nutrition and Food Security Research Center and diabetes research center of Shahid Sadoughi University of Medical Sciences, Yazd, Iran, for their scientific support and close cooperation, respectively. The trial has been registered in the Iranian registry of clinical trials as IRCT2016091312571N6 (http://en.irct.ir/trial/12622). The current study was funded by Shahid Sadoughi University of Medical Sciences (http://www.ssu.ac.ir) and Neshatavar food industry (Datis Corporation; http://www.neshatavar.com/?l=EN). Datis Corporation also provided all of the treatment oils consumed during the study, including canola, sesame, sesame-canola and sunflower oils. Datis Corporation had no role in the design and conduct of this manuscript; collection, management, analysis and interpretation of the data; and preparation of this manuscript.
Publisher Copyright:
© 2021 Society of Chemical Industry.
PY - 2021/11
Y1 - 2021/11
N2 - BACKGROUND: Recent investigations have proposed that sesame and canola oils might affect body fat distribution. The present study aimed to examine the effects of sesame, canola and sesame-canola (a blend of sesame and canola oils) oils on body weight and composition in adults with type 2 diabetes mellitus in the context of a randomized, triple-blind, three-way, cross-over clinical trial. RESULTS: Eligible participants were randomized to replace their regular dietary oil with sesame oil (SO), canola oil (CO) and sesame-canola oil (SCO) (with 40% SO and 60% CO). Treatment periods lasted 9 weeks and were separated by 4-week wash-out periods. Body weight and composition were measured at the beginning, in the middle and at the end of each intervention phase. In total, 93 participants completed the study. After adjustment for confounders, within-period changes were observed following SO and CO intake for body weight (0.34 ± 0.16 kg and 0.33 ± 0.17 kg) and visceral fat (0.13 ± 0.06% and 0.13 ± 0.05%, P < 0.05), respectively. Body mass index was increased within SO intake (0.13 ± 0.05 kg m−2, P = 0.031). All of the treatment oils resulted in reduced waist circumference and index of central obesity (P < 0.05). A significant difference in change values was observed for visceral fat between SCO (−0.14 ± 0.07%) and SO (0.12 ± 0.08%) treatment periods in females (P = 0.02). CONCLUSION: Sesame and canola oils might lead to a modest favorable body fat redistribution by reducing central adiposity, particularly in females; however, the changes were of little clinical importance.
AB - BACKGROUND: Recent investigations have proposed that sesame and canola oils might affect body fat distribution. The present study aimed to examine the effects of sesame, canola and sesame-canola (a blend of sesame and canola oils) oils on body weight and composition in adults with type 2 diabetes mellitus in the context of a randomized, triple-blind, three-way, cross-over clinical trial. RESULTS: Eligible participants were randomized to replace their regular dietary oil with sesame oil (SO), canola oil (CO) and sesame-canola oil (SCO) (with 40% SO and 60% CO). Treatment periods lasted 9 weeks and were separated by 4-week wash-out periods. Body weight and composition were measured at the beginning, in the middle and at the end of each intervention phase. In total, 93 participants completed the study. After adjustment for confounders, within-period changes were observed following SO and CO intake for body weight (0.34 ± 0.16 kg and 0.33 ± 0.17 kg) and visceral fat (0.13 ± 0.06% and 0.13 ± 0.05%, P < 0.05), respectively. Body mass index was increased within SO intake (0.13 ± 0.05 kg m−2, P = 0.031). All of the treatment oils resulted in reduced waist circumference and index of central obesity (P < 0.05). A significant difference in change values was observed for visceral fat between SCO (−0.14 ± 0.07%) and SO (0.12 ± 0.08%) treatment periods in females (P = 0.02). CONCLUSION: Sesame and canola oils might lead to a modest favorable body fat redistribution by reducing central adiposity, particularly in females; however, the changes were of little clinical importance.
KW - body composition
KW - body weight
KW - canola oil
KW - dietary oils
KW - sesame oil
KW - type 2 diabetes mellitus
UR - http://www.scopus.com/inward/record.url?scp=85106432311&partnerID=8YFLogxK
U2 - 10.1002/jsfa.11265
DO - 10.1002/jsfa.11265
M3 - Article
C2 - 33899246
AN - SCOPUS:85106432311
SN - 0022-5142
VL - 101
SP - 6083
EP - 6092
JO - Journal of the Science of Food and Agriculture
JF - Journal of the Science of Food and Agriculture
IS - 14
ER -