Abstract
We used data of 32,542 prospective cohort study participants who previously received primary and one or two monovalent booster COVID-19 vaccinations. Between 26 September and 19 December 2022, relative effectiveness of bivalent original/Omicron BA.1 vaccination against self-reported Omicron SARS-CoV-2 infection was 31% in 18-59-year-olds and 14% in 60-85-year-olds. Protection of Omicron infection was higher than of bivalent vaccination without prior infection. Although bivalent booster vaccination increases protection against COVID-19 hospitalisations, we found limited added benefit in preventing SARS-CoV-2 infection.
Original language | English |
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Journal | Eurosurveillance |
Volume | 28 |
Issue number | 7 |
DOIs | |
Publication status | Published - 16 Feb 2023 |
Keywords
- COVID-19
- SARS-CoV-2
- vaccine effectiveness