Abstract
The effect of scaffold architecture on composition of tissue engineered cartilage was discussed. Two processing techniques, compression-molding / particulate-leaching (CM) and three dimensional fiber deposition (3DF), were used to develop porous scaffolds from biodegradable poly(ethylene glycol)-terephthalate/poly(butylene terephthalate (PEGT/PBT) co-polymers with varying pore architectures. Three-dimensional micro-computed tomography (μCT) was used to characterize scaffold architectures and scaffolds were seeded with articular chondrocytes to evaluate tissue formation. Highly interconnected 3DF scaffolds create an environment in vivo that enhances deposition of matrix with resemblance to native cartilage tissue.
Original language | English |
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Title of host publication | Transactions - 7th World Biomaterials Congress |
Number of pages | 1 |
Publication status | Published - 1 Dec 2004 |
Event | Transactions - 7th World Biomaterials Congress - Sydney, Australia Duration: 17 May 2004 → 21 May 2004 |
Conference
Conference | Transactions - 7th World Biomaterials Congress |
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Country/Territory | Australia |
City | Sydney |
Period | 17/05/04 → 21/05/04 |