TY - JOUR
T1 - Effect of a novel endoscope cleaning brush on duodenoscope contamination
AU - Van Der Ploeg, Koen
AU - Haanappel, Cynthia P.
AU - Voor In 'T Holt, Anne F.
AU - De Groot, Woutrinus
AU - Bulkmans, Adriana J.C.
AU - Erler, Nicole S.
AU - Mason-Slingerland, Bibi C.G.C.
AU - Vos, Margreet C.
AU - Bruno, Marco J.
AU - Severin, Juliëtte A.
N1 - Publisher Copyright:
© 2023. The Author(s).
PY - 2023/5/25
Y1 - 2023/5/25
N2 - Background Current duodenoscope reprocessing protocols are insufficient to prevent contamination and require adaptations to prevent endoscopy-associated infections (EAIs). This study aimed to investigate the effect of a new endoscope cleaning brush on the contamination rate of ready-to-use duodenoscopes. Methods This retrospective before-and-after intervention study collected duodenoscope surveillance culture results from March 2018 to June 2022. Contamination was defined as .1 colony-forming unit of a microorganism of gut or oral origin (MGO). In December 2020, an endoscope cleaning brush with a sweeper design was introduced as an intervention in the manual cleaning of duodenoscopes. A logistic mixed-effects model was used to study the effects of this intervention. Results Data were collected from 176 culture sets before the new brush's introduction and 81 culture sets afterwards. Pre-introduction, culture sets positive with an MGO comprised 45.5% (95%CI 38.3%.52.8%; 80/176), decreasing to 17.3% (95%CI 10.6%.26.9%; 14/81) after implementation of the new brush. Compared with the former brush, duodenoscopes cleaned with the new brush had lower odds of contamination with MGOs (adjusted odds ratio 0.25, 95% CI 0.11.0.58; P=0.001) Conclusions Use of the new brush in manual cleaning reduced contamination with MGOs and is expected to prevent EAIs. These findings should be confirmed in future prospective randomized studies.
AB - Background Current duodenoscope reprocessing protocols are insufficient to prevent contamination and require adaptations to prevent endoscopy-associated infections (EAIs). This study aimed to investigate the effect of a new endoscope cleaning brush on the contamination rate of ready-to-use duodenoscopes. Methods This retrospective before-and-after intervention study collected duodenoscope surveillance culture results from March 2018 to June 2022. Contamination was defined as .1 colony-forming unit of a microorganism of gut or oral origin (MGO). In December 2020, an endoscope cleaning brush with a sweeper design was introduced as an intervention in the manual cleaning of duodenoscopes. A logistic mixed-effects model was used to study the effects of this intervention. Results Data were collected from 176 culture sets before the new brush's introduction and 81 culture sets afterwards. Pre-introduction, culture sets positive with an MGO comprised 45.5% (95%CI 38.3%.52.8%; 80/176), decreasing to 17.3% (95%CI 10.6%.26.9%; 14/81) after implementation of the new brush. Compared with the former brush, duodenoscopes cleaned with the new brush had lower odds of contamination with MGOs (adjusted odds ratio 0.25, 95% CI 0.11.0.58; P=0.001) Conclusions Use of the new brush in manual cleaning reduced contamination with MGOs and is expected to prevent EAIs. These findings should be confirmed in future prospective randomized studies.
UR - http://www.scopus.com/inward/record.url?scp=85174973032&partnerID=8YFLogxK
U2 - 10.1055/a-2193-4481
DO - 10.1055/a-2193-4481
M3 - Article
C2 - 37848074
AN - SCOPUS:85174973032
SN - 0013-726X
VL - 56
SP - 198
EP - 204
JO - Endoscopy
JF - Endoscopy
IS - 3
ER -