Early COVID-19 vaccine effectiveness of XBB.1.5 vaccine against hospitalisation and admission to intensive care, the Netherlands, 9 October to 5 December 2023

C. Henri van Werkhoven; Anne Wil Valk; Bente Smagge; Hester E. de Melker; Mirjam J. Knol; Susan JM Hahné; Susan van den Hof; Brechje de Gier

doi:10.2807/1560-7917.ES.2024.29.1.2300703

Early COVID-19 vaccine effectiveness of XBB.1.5 vaccine against hospitalisation and admission to intensive care, the Netherlands, 9 October to 5 December 2023

C. Henri van Werkhoven, Anne Wil Valk, Bente Smagge, Hester E. de Melker, Mirjam J. Knol, Susan JM Hahné, Susan van den Hof, Brechje de Gier^*

^*Corresponding author for this work

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Abstract

We present early vaccine effectiveness (VE) estimates of the 2023 seasonal COVID-19 XBB.1.5 vaccine against COVID-19 hospitalisation and admission to an intensive care unit (ICU) in previously vaccinated adults≥60 years in the Netherlands. We compared vaccination status of 2,050 hospitalisations including 92 ICU admissions with age group-, sex-, region- and date-specific population vaccination coverage between 9 October and 5 December 2023. VE against hospitalisation was 70.7% (95% CI: 66.6–74.3), VE against ICU admission was 73.3% (95% CI: 42.2–87.6).

Original language	English
Article number	2300703
Journal	Eurosurveillance
Volume	29
Issue number	1
DOIs	https://doi.org/10.2807/1560-7917.ES.2024.29.1.2300703
Publication status	Published - 4 Jan 2024

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eurosurv-29-1-1Final published version, 189 KBLicence: CC BY

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van Werkhoven, C. H., Valk, A. W., Smagge, B., de Melker, H. E., Knol, M. J., Hahné, S. JM., van den Hof, S., & de Gier, B. (2024). Early COVID-19 vaccine effectiveness of XBB.1.5 vaccine against hospitalisation and admission to intensive care, the Netherlands, 9 October to 5 December 2023. Eurosurveillance, 29(1), Article 2300703. https://doi.org/10.2807/1560-7917.ES.2024.29.1.2300703

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title = "Early COVID-19 vaccine effectiveness of XBB.1.5 vaccine against hospitalisation and admission to intensive care, the Netherlands, 9 October to 5 December 2023",

abstract = "We present early vaccine effectiveness (VE) estimates of the 2023 seasonal COVID-19 XBB.1.5 vaccine against COVID-19 hospitalisation and admission to an intensive care unit (ICU) in previously vaccinated adults≥60 years in the Netherlands. We compared vaccination status of 2,050 hospitalisations including 92 ICU admissions with age group-, sex-, region- and date-specific population vaccination coverage between 9 October and 5 December 2023. VE against hospitalisation was 70.7% (95% CI: 66.6–74.3), VE against ICU admission was 73.3% (95% CI: 42.2–87.6).",

author = "{van Werkhoven}, {C. Henri} and Valk, {Anne Wil} and Bente Smagge and {de Melker}, {Hester E.} and Knol, {Mirjam J.} and Hahn{\'e}, {Susan JM} and {van den Hof}, Susan and {de Gier}, Brechje",

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van Werkhoven, CH, Valk, AW, Smagge, B, de Melker, HE, Knol, MJ, Hahné, SJM, van den Hof, S & de Gier, B 2024, 'Early COVID-19 vaccine effectiveness of XBB.1.5 vaccine against hospitalisation and admission to intensive care, the Netherlands, 9 October to 5 December 2023', Eurosurveillance, vol. 29, no. 1, 2300703. https://doi.org/10.2807/1560-7917.ES.2024.29.1.2300703

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AU - van Werkhoven, C. Henri

AU - Valk, Anne Wil

AU - Smagge, Bente

AU - de Melker, Hester E.

AU - Knol, Mirjam J.

AU - Hahné, Susan JM

AU - van den Hof, Susan

AU - de Gier, Brechje

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N2 - We present early vaccine effectiveness (VE) estimates of the 2023 seasonal COVID-19 XBB.1.5 vaccine against COVID-19 hospitalisation and admission to an intensive care unit (ICU) in previously vaccinated adults≥60 years in the Netherlands. We compared vaccination status of 2,050 hospitalisations including 92 ICU admissions with age group-, sex-, region- and date-specific population vaccination coverage between 9 October and 5 December 2023. VE against hospitalisation was 70.7% (95% CI: 66.6–74.3), VE against ICU admission was 73.3% (95% CI: 42.2–87.6).

AB - We present early vaccine effectiveness (VE) estimates of the 2023 seasonal COVID-19 XBB.1.5 vaccine against COVID-19 hospitalisation and admission to an intensive care unit (ICU) in previously vaccinated adults≥60 years in the Netherlands. We compared vaccination status of 2,050 hospitalisations including 92 ICU admissions with age group-, sex-, region- and date-specific population vaccination coverage between 9 October and 5 December 2023. VE against hospitalisation was 70.7% (95% CI: 66.6–74.3), VE against ICU admission was 73.3% (95% CI: 42.2–87.6).

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Early COVID-19 vaccine effectiveness of XBB.1.5 vaccine against hospitalisation and admission to intensive care, the Netherlands, 9 October to 5 December 2023

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