Distant metastases from head and neck squamous cell carcinoma. Part III. Treatment

Missak Haigentz; Dana M. Hartl; Carl E. Silver; Johannes A. Langendijk; Primož Strojan; Vinidh Paleri; Remco De Bree; Jean Pascal MacHiels; Marc Hamoir; Alessandra Rinaldo; Daniela Paccagnella; Ashok R. Shaha; Robert P. Takes; Alfio Ferlito

doi:10.1016/j.oraloncology.2012.03.019

Distant metastases from head and neck squamous cell carcinoma. Part III. Treatment

Missak Haigentz
, Dana M. Hartl
, Carl E. Silver
, Johannes A. Langendijk
, Primož Strojan
, Vinidh Paleri
, Remco De Bree
, Jean Pascal MacHiels
, Marc Hamoir
, Alessandra Rinaldo
, Daniela Paccagnella
, Ashok R. Shaha
, Robert P. Takes
, Alfio Ferlito^*

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

28 Citations (Scopus)

Abstract

Distant metastases from head and neck squamous cell carcinoma (HNSCC), though rare at initial presentation, remain an important manifestation of cancer recurrence and mortality. Although generally considered incurable with a dismal prognosis despite palliative therapy, highly selected patients with distant metastases may have a long term survival benefit from aggressive surgery or radiotherapy. Advances in systemic treatments also may improve patient survival. This article reviews the current state of management of HNSCC patients with distant metastases.

Original language	English
Pages (from-to)	787-793
Number of pages	7
Journal	Oral Oncology
Volume	48
Issue number	9
DOIs	https://doi.org/10.1016/j.oraloncology.2012.03.019
Publication status	Published - 1 Sept 2012

Keywords

Chemotherapy
Distant metastases
Head and neck squamous cell carcinoma
Metastasectomy
Treatment

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10.1016/j.oraloncology.2012.03.019

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Haigentz, M., Hartl, D. M., Silver, C. E., Langendijk, J. A., Strojan, P., Paleri, V., De Bree, R., MacHiels, J. P., Hamoir, M., Rinaldo, A., Paccagnella, D., Shaha, A. R., Takes, R. P., & Ferlito, A. (2012). Distant metastases from head and neck squamous cell carcinoma. Part III. Treatment. Oral Oncology, 48(9), 787-793. https://doi.org/10.1016/j.oraloncology.2012.03.019

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title = "Distant metastases from head and neck squamous cell carcinoma. Part III. Treatment",

abstract = "Distant metastases from head and neck squamous cell carcinoma (HNSCC), though rare at initial presentation, remain an important manifestation of cancer recurrence and mortality. Although generally considered incurable with a dismal prognosis despite palliative therapy, highly selected patients with distant metastases may have a long term survival benefit from aggressive surgery or radiotherapy. Advances in systemic treatments also may improve patient survival. This article reviews the current state of management of HNSCC patients with distant metastases.",

keywords = "Chemotherapy, Distant metastases, Head and neck squamous cell carcinoma, Metastasectomy, Treatment",

author = "Missak Haigentz and Hartl, \{Dana M.\} and Silver, \{Carl E.\} and Langendijk, \{Johannes A.\} and Primo{\v z} Strojan and Vinidh Paleri and \{De Bree\}, Remco and MacHiels, \{Jean Pascal\} and Marc Hamoir and Alessandra Rinaldo and Daniela Paccagnella and Shaha, \{Ashok R.\} and Takes, \{Robert P.\} and Alfio Ferlito",

year = "2012",

month = sep,

day = "1",

doi = "10.1016/j.oraloncology.2012.03.019",

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T1 - Distant metastases from head and neck squamous cell carcinoma. Part III. Treatment

AU - Haigentz, Missak

AU - Hartl, Dana M.

AU - Silver, Carl E.

AU - Langendijk, Johannes A.

AU - Strojan, Primož

AU - Paleri, Vinidh

AU - De Bree, Remco

AU - MacHiels, Jean Pascal

AU - Hamoir, Marc

AU - Rinaldo, Alessandra

AU - Paccagnella, Daniela

AU - Shaha, Ashok R.

AU - Takes, Robert P.

AU - Ferlito, Alfio

PY - 2012/9/1

Y1 - 2012/9/1

N2 - Distant metastases from head and neck squamous cell carcinoma (HNSCC), though rare at initial presentation, remain an important manifestation of cancer recurrence and mortality. Although generally considered incurable with a dismal prognosis despite palliative therapy, highly selected patients with distant metastases may have a long term survival benefit from aggressive surgery or radiotherapy. Advances in systemic treatments also may improve patient survival. This article reviews the current state of management of HNSCC patients with distant metastases.

AB - Distant metastases from head and neck squamous cell carcinoma (HNSCC), though rare at initial presentation, remain an important manifestation of cancer recurrence and mortality. Although generally considered incurable with a dismal prognosis despite palliative therapy, highly selected patients with distant metastases may have a long term survival benefit from aggressive surgery or radiotherapy. Advances in systemic treatments also may improve patient survival. This article reviews the current state of management of HNSCC patients with distant metastases.

KW - Chemotherapy

KW - Distant metastases

KW - Head and neck squamous cell carcinoma

KW - Metastasectomy

KW - Treatment

UR - https://www.scopus.com/pages/publications/84865174102

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DO - 10.1016/j.oraloncology.2012.03.019

M3 - Review article

C2 - 22516376

AN - SCOPUS:84865174102

SN - 1368-8375

VL - 48

SP - 787

EP - 793

JO - Oral Oncology

JF - Oral Oncology

IS - 9

ER -

Distant metastases from head and neck squamous cell carcinoma. Part III. Treatment

Abstract

Keywords

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