Discovery of biomarkers for the presence and progression of left ventricular diastolic dysfunction and HEart faiLure with Preserved ejection Fraction in patients at risk for cardiovascular disease: rationale and design of the HELPFul case-cohort study in a Dutch cardiology outpatient clinic

Gideon B Valstar, Sophie H Bots, Floor Groepenhoff, Aisha Gohar, Frans H Rutten, Tim Leiner, Maarten Jan Maria Cramer, Arco J Teske, Leonardo P Suciadi, Roxana Menken, Gerard Pasterkamp, Folkert W Asselbergs, Leonard Hofstra, Michael L Bots, Hester M den Ruijter

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