Diffusion weighted MR imaging to evaluate treatment results after volumetric MR-guided high intensity focused ultrasound of uterine fibroids: Influence of different b-values

M. J. Voogt*, B. Keserci, Y. S. Kim, H. Rhim, H. K. Lim, C. Mougenot, M. O. Kohler, M. A. Van Den Bosch, K. L. Vincken, L. W. Bartels

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

1 Citation (Scopus)

Abstract

We have assessed the feasibility of using diffusion weighted MR imaging (DWI) and apparent diffusion coefficient (ADC) mapping using different b-value combinations to evaluate treatment results after volumetric magnetic resonance-guided high intensity focused ultrasound (MR-HIFU) for uterine fibroids. Pre-treatment, directly post-treatment and 1 month follow-up DW images were obtained using b-values 0, 200, 400, 600 and 800 s/mm 2 . ADC maps were constructed for quantitative analysis of ablation results. Four different combinations of b-values were used to calculate the ADC. Directly after treatment ADC values decreased. Low b-values (0 and 200 s/mm 2 ) resulted in the best contrast between non-perfused and perfused tissue. One month after treatment the average ADC was increased, now showing the best contrast on the high b-value ADC maps.

Original languageEnglish
Title of host publication10th International Symposium on Therapeutic Ultrasound, ISTU 2010
Pages483-487
Number of pages5
DOIs
Publication statusPublished - 13 Oct 2011
Event10th International Symposium on Therapeutic Ultrasound, ISTU 2010 - Tokyo, Japan
Duration: 9 Jun 201012 Jun 2010

Publication series

NameAIP Conference Proceedings
Volume1359
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Conference

Conference10th International Symposium on Therapeutic Ultrasound, ISTU 2010
Country/TerritoryJapan
CityTokyo
Period9/06/1012/06/10

Keywords

  • Apparent diffusion coefficient
  • Diffusion weighted imaging
  • MR-guided High Intensity Focused Ultrasound
  • Uterine fibroids

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