Differential Association of Anthropometric Parameters with Coronary Risk in Women - Data of the CORA Study

Birgit-Christiane Zyriax; Mark Schoeffauer; Kerstin Klipstein-Grobusch; Heiner Boeing; Eberhard Windler

doi:10.1159/000333964

Differential Association of Anthropometric Parameters with Coronary Risk in Women - Data of the CORA Study

Birgit-Christiane Zyriax^*, Mark Schoeffauer, Kerstin Klipstein-Grobusch, Heiner Boeing, Eberhard Windler

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Objective: The predictive value of weight gain, BMI, waist circumference (WC) and waist-to-hip ratio (WHR) as to cardiovascular risk factors and coronary heart disease (CHD) is still controversial. Methods: 200 consecutive pre- and postmenopausal women with incident CHD (cases) were compared with 255 randomized age-matched population-based controls recruited from corresponding neighborhoods of Hamburg between 1997 and 2001. Results: At the time of recruitment cases and controls did not differ in BMI, but at any BMI in WC and WHR. Both parameters of central obesity were related to coronary risk. However, after adjustment for conventional risk factors, the odds ratio of WC for CHD lost its significance while the odds ratio of WHR was still 2.20 per 0.1 unit (95% confidence interval 1.48-3.27; p = 0.0001). The pattern of weight gain differed considerably in women with WHR >= 0.85 or

Original language	English
Pages (from-to)	358-364
Number of pages	7
Journal	Obesity Facts
Volume	4
Issue number	5
DOIs	https://doi.org/10.1159/000333964
Publication status	Published - Oct 2011

Keywords

Weight gain
Waist circumference
Waist-to-hip ratio
Central obesity
Coronary heart disease
Metabolic syndrome
BODY-MASS INDEX
CARDIOVASCULAR-DISEASE
WEIGHT CHANGE
HEART-DISEASE
WAIST CIRCUMFERENCE
METABOLIC SYNDROME
ABDOMINAL OBESITY
HIP RATIO
MEN
AGE

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10.1159/000333964

http://www.ncbi.nlm.nih.gov/pubmed/22166755

Cite this

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title = "Differential Association of Anthropometric Parameters with Coronary Risk in Women - Data of the CORA Study",

abstract = "Objective: The predictive value of weight gain, BMI, waist circumference (WC) and waist-to-hip ratio (WHR) as to cardiovascular risk factors and coronary heart disease (CHD) is still controversial. Methods: 200 consecutive pre- and postmenopausal women with incident CHD (cases) were compared with 255 randomized age-matched population-based controls recruited from corresponding neighborhoods of Hamburg between 1997 and 2001. Results: At the time of recruitment cases and controls did not differ in BMI, but at any BMI in WC and WHR. Both parameters of central obesity were related to coronary risk. However, after adjustment for conventional risk factors, the odds ratio of WC for CHD lost its significance while the odds ratio of WHR was still 2.20 per 0.1 unit (95% confidence interval 1.48-3.27; p = 0.0001). The pattern of weight gain differed considerably in women with WHR >= 0.85 or",

keywords = "Weight gain, Waist circumference, Waist-to-hip ratio, Central obesity, Coronary heart disease, Metabolic syndrome, BODY-MASS INDEX, CARDIOVASCULAR-DISEASE, WEIGHT CHANGE, HEART-DISEASE, WAIST CIRCUMFERENCE, METABOLIC SYNDROME, ABDOMINAL OBESITY, HIP RATIO, MEN, AGE",

author = "Birgit-Christiane Zyriax and Mark Schoeffauer and Kerstin Klipstein-Grobusch and Heiner Boeing and Eberhard Windler",

year = "2011",

month = oct,

doi = "10.1159/000333964",

language = "English",

volume = "4",

pages = "358--364",

journal = "Obesity Facts",

issn = "1662-4025",

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T1 - Differential Association of Anthropometric Parameters with Coronary Risk in Women - Data of the CORA Study

AU - Zyriax, Birgit-Christiane

AU - Schoeffauer, Mark

AU - Klipstein-Grobusch, Kerstin

AU - Boeing, Heiner

AU - Windler, Eberhard

PY - 2011/10

Y1 - 2011/10

N2 - Objective: The predictive value of weight gain, BMI, waist circumference (WC) and waist-to-hip ratio (WHR) as to cardiovascular risk factors and coronary heart disease (CHD) is still controversial. Methods: 200 consecutive pre- and postmenopausal women with incident CHD (cases) were compared with 255 randomized age-matched population-based controls recruited from corresponding neighborhoods of Hamburg between 1997 and 2001. Results: At the time of recruitment cases and controls did not differ in BMI, but at any BMI in WC and WHR. Both parameters of central obesity were related to coronary risk. However, after adjustment for conventional risk factors, the odds ratio of WC for CHD lost its significance while the odds ratio of WHR was still 2.20 per 0.1 unit (95% confidence interval 1.48-3.27; p = 0.0001). The pattern of weight gain differed considerably in women with WHR >= 0.85 or

AB - Objective: The predictive value of weight gain, BMI, waist circumference (WC) and waist-to-hip ratio (WHR) as to cardiovascular risk factors and coronary heart disease (CHD) is still controversial. Methods: 200 consecutive pre- and postmenopausal women with incident CHD (cases) were compared with 255 randomized age-matched population-based controls recruited from corresponding neighborhoods of Hamburg between 1997 and 2001. Results: At the time of recruitment cases and controls did not differ in BMI, but at any BMI in WC and WHR. Both parameters of central obesity were related to coronary risk. However, after adjustment for conventional risk factors, the odds ratio of WC for CHD lost its significance while the odds ratio of WHR was still 2.20 per 0.1 unit (95% confidence interval 1.48-3.27; p = 0.0001). The pattern of weight gain differed considerably in women with WHR >= 0.85 or

KW - Weight gain

KW - Waist circumference

KW - Waist-to-hip ratio

KW - Central obesity

KW - Coronary heart disease

KW - Metabolic syndrome

KW - BODY-MASS INDEX

KW - CARDIOVASCULAR-DISEASE

KW - WEIGHT CHANGE

KW - HEART-DISEASE

KW - WAIST CIRCUMFERENCE

KW - METABOLIC SYNDROME

KW - ABDOMINAL OBESITY

KW - HIP RATIO

KW - MEN

KW - AGE

U2 - 10.1159/000333964

DO - 10.1159/000333964

M3 - Article

C2 - 22166755

SN - 1662-4025

VL - 4

SP - 358

EP - 364

JO - Obesity Facts

JF - Obesity Facts

IS - 5

ER -

Differential Association of Anthropometric Parameters with Coronary Risk in Women - Data of the CORA Study

Abstract

Keywords

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