Diagnostic accuracy of Tc-99m DMSA scintigraphy and renal ultrasonography for detecting renal scarring and relative function in patients with spinal dysraphism

Paul W. Veenboer; Monique G G  Hobbelink; J.L.H. Ruud  Bosch; Pieter  Dik; Floris W A Van Asbeck; Frederik J A Beek; Laetitia M.O. de Kort

doi:10.1002/nau.22608

Diagnostic accuracy of Tc-99m DMSA scintigraphy and renal ultrasonography for detecting renal scarring and relative function in patients with spinal dysraphism

Paul W. Veenboer^*, Monique G G Hobbelink, J.L.H. Ruud Bosch, Pieter Dik, Floris W A Van Asbeck, Frederik J A Beek, Laetitia M.O. de Kort

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

Aims To study additional benefits of performing Tc-99m dimercaptosuccinic acid (Tc-99m-DMSA) scintigraphy as part of the follow-up of adults with spinal dysraphism (SD), compared with ultrasonography, with regard to finding renal scarring and difference in split renal function. Methods Between January 2011 and April 2013 every patient visiting our specialized outpatient clinic for adults with SD was invited to undergo both renal ultrasonography and Tc-99m-DMSA scintigraphy. Outcomes of both modalities were compared, with focus on renal scarring. The relation between renal scarring and hypertension was also assessed. Results In total, 122 patients (with 242 renal units) underwent both renal scintigraphy and ultrasonography. More scars were seen on DMSA scintigraphy than on ultrasonography: 45.9% vs. 10.3% of renal units; P

Original language	English
Pages (from-to)	513-518
Number of pages	6
Journal	Neurourology and Urodynamics
Volume	34
Issue number	6
DOIs	https://doi.org/10.1002/nau.22608
Publication status	Published - Aug 2015

Keywords

DMSA
neurogenic bladder
scintigraphy
sensitivity and specificity
spina bifida
ultrasonography
ultrasound

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10.1002/nau.22608

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Veenboer, P. W., Hobbelink, M. G. G., Bosch, J. L. H. R., Dik, P., Van Asbeck, F. W. A., Beek, F. J. A., & de Kort, L. M. O. (2015). Diagnostic accuracy of Tc-99m DMSA scintigraphy and renal ultrasonography for detecting renal scarring and relative function in patients with spinal dysraphism. Neurourology and Urodynamics, 34(6), 513-518. https://doi.org/10.1002/nau.22608

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title = "Diagnostic accuracy of Tc-99m DMSA scintigraphy and renal ultrasonography for detecting renal scarring and relative function in patients with spinal dysraphism",

abstract = "Aims To study additional benefits of performing Tc-99m dimercaptosuccinic acid (Tc-99m-DMSA) scintigraphy as part of the follow-up of adults with spinal dysraphism (SD), compared with ultrasonography, with regard to finding renal scarring and difference in split renal function. Methods Between January 2011 and April 2013 every patient visiting our specialized outpatient clinic for adults with SD was invited to undergo both renal ultrasonography and Tc-99m-DMSA scintigraphy. Outcomes of both modalities were compared, with focus on renal scarring. The relation between renal scarring and hypertension was also assessed. Results In total, 122 patients (with 242 renal units) underwent both renal scintigraphy and ultrasonography. More scars were seen on DMSA scintigraphy than on ultrasonography: 45.9% vs. 10.3% of renal units; P",

keywords = "DMSA, neurogenic bladder, scintigraphy, sensitivity and specificity, spina bifida, ultrasonography, ultrasound",

author = "Veenboer, {Paul W.} and Hobbelink, {Monique G G} and Bosch, {J.L.H. Ruud} and Pieter Dik and {Van Asbeck}, {Floris W A} and Beek, {Frederik J A} and {de Kort}, {Laetitia M.O.}",

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Diagnostic accuracy of Tc-99m DMSA scintigraphy and renal ultrasonography for detecting renal scarring and relative function in patients with spinal dysraphism. / Veenboer, Paul W.; Hobbelink, Monique G G ; Bosch, J.L.H. Ruud et al.
In: Neurourology and Urodynamics, Vol. 34, No. 6, 08.2015, p. 513-518.

Research output: Contribution to journal › Article › Academic › peer-review

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AU - Dik, Pieter

AU - Van Asbeck, Floris W A

AU - Beek, Frederik J A

AU - de Kort, Laetitia M.O.

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Diagnostic accuracy of Tc-99m DMSA scintigraphy and renal ultrasonography for detecting renal scarring and relative function in patients with spinal dysraphism

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