Dexamethasone treatment has no effect on the formation of pneumococcal antibodies during community-acquired pneumonia

Suzan P van Mens; Sabine C A Meijvis; Jan C Grutters; Bart J M Vlaminckx; Willem J W Bos; Ger T Rijkers

doi:10.1128/CVI.05697-11

Dexamethasone treatment has no effect on the formation of pneumococcal antibodies during community-acquired pneumonia

Suzan P van Mens, Sabine C A Meijvis, Jan C Grutters, Bart J M Vlaminckx, Willem J W Bos, Ger T Rijkers

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

In this study, the effect of dexamethasone on the formation of pneumococcal antibodies during community-acquired pneumonia (CAP) was investigated. No differences between CAP patients receiving dexamethasone as additional therapy and patients receiving a placebo were found with respect to immune response rates and mean baseline and convalescent-phase antibody concentrations.

Original language	English
Pages (from-to)	811-813
Number of pages	3
Journal	Clinical and Vaccine Immunology
Volume	19
Issue number	5
DOIs	https://doi.org/10.1128/CVI.05697-11
Publication status	Published - 2012

Keywords

Adult
Aged
Aged, 80 and over
Antibodies, Bacterial
Antineoplastic Agents
Community-Acquired Infections
Dexamethasone
Double-Blind Method
Female
Humans
Male
Middle Aged
Placebos
Pneumonia, Pneumococcal
Journal Article
Randomized Controlled Trial

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10.1128/CVI.05697-11

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title = "Dexamethasone treatment has no effect on the formation of pneumococcal antibodies during community-acquired pneumonia",

abstract = "In this study, the effect of dexamethasone on the formation of pneumococcal antibodies during community-acquired pneumonia (CAP) was investigated. No differences between CAP patients receiving dexamethasone as additional therapy and patients receiving a placebo were found with respect to immune response rates and mean baseline and convalescent-phase antibody concentrations.",

keywords = "Adult, Aged, Aged, 80 and over, Antibodies, Bacterial, Antineoplastic Agents, Community-Acquired Infections, Dexamethasone, Double-Blind Method, Female, Humans, Male, Middle Aged, Placebos, Pneumonia, Pneumococcal, Journal Article, Randomized Controlled Trial",

author = "\{van Mens\}, \{Suzan P\} and Meijvis, \{Sabine C A\} and Grutters, \{Jan C\} and Vlaminckx, \{Bart J M\} and Bos, \{Willem J W\} and Rijkers, \{Ger T\}",

year = "2012",

doi = "10.1128/CVI.05697-11",

language = "English",

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journal = "Clinical and Vaccine Immunology",

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publisher = "American Society for Microbiology",

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T1 - Dexamethasone treatment has no effect on the formation of pneumococcal antibodies during community-acquired pneumonia

AU - van Mens, Suzan P

AU - Meijvis, Sabine C A

AU - Grutters, Jan C

AU - Vlaminckx, Bart J M

AU - Bos, Willem J W

AU - Rijkers, Ger T

PY - 2012

Y1 - 2012

N2 - In this study, the effect of dexamethasone on the formation of pneumococcal antibodies during community-acquired pneumonia (CAP) was investigated. No differences between CAP patients receiving dexamethasone as additional therapy and patients receiving a placebo were found with respect to immune response rates and mean baseline and convalescent-phase antibody concentrations.

AB - In this study, the effect of dexamethasone on the formation of pneumococcal antibodies during community-acquired pneumonia (CAP) was investigated. No differences between CAP patients receiving dexamethasone as additional therapy and patients receiving a placebo were found with respect to immune response rates and mean baseline and convalescent-phase antibody concentrations.

KW - Adult

KW - Aged

KW - Aged, 80 and over

KW - Antibodies, Bacterial

KW - Antineoplastic Agents

KW - Community-Acquired Infections

KW - Dexamethasone

KW - Double-Blind Method

KW - Female

KW - Humans

KW - Male

KW - Middle Aged

KW - Placebos

KW - Pneumonia, Pneumococcal

KW - Journal Article

KW - Randomized Controlled Trial

U2 - 10.1128/CVI.05697-11

DO - 10.1128/CVI.05697-11

M3 - Article

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SN - 1556-6811

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SP - 811

EP - 813

JO - Clinical and Vaccine Immunology

JF - Clinical and Vaccine Immunology

IS - 5

ER -

Dexamethasone treatment has no effect on the formation of pneumococcal antibodies during community-acquired pneumonia

Abstract

Keywords

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