Abstract
UNLABELLED: The uptake of 2-deoxy-2-[18F]fluoro-D-glucose (FDG) in neck lymph nodes of twelve patients with a squamous-cell carcinoma of the oral cavity was studied with PET in order to detect and locate lymphogenic metastases.
METHODS: The results of FDG-PET imaging were compared with clinical, MRI and histopathologic findings. Standardized uptake values (SUV) were also calculated.
RESULTS: A sensitivity of 91% and a specificity of 88% were calculated for FDG-PET. In contrast, a sensitivity of 36% and a specificity of 94% were calculated for MRI. Calculated SUVs for reactive lymph nodes, metastatic lymph nodes and the primary tumor were undifferentiated.
CONCLUSION: Using FDG-PET, lymph node metastases of squamous-cell carcinomas of the oral cavity can be visualized with a high sensitivity and specificity. FDG-PET can be an improvement in the evaluation of the neck.
| Original language | English |
|---|---|
| Pages (from-to) | 211-6 |
| Number of pages | 6 |
| Journal | Journal of Nuclear Medicine |
| Volume | 36 |
| Issue number | 2 |
| Publication status | Published - Feb 1995 |
Keywords
- Aged
- Aged, 80 and over
- Carcinoma, Squamous Cell
- Deoxyglucose
- Female
- Fluorine Radioisotopes
- Fluorodeoxyglucose F18
- Head and Neck Neoplasms
- Humans
- Lymph Nodes
- Lymphatic Metastasis
- Magnetic Resonance Imaging
- Male
- Middle Aged
- Mouth Neoplasms