Abstract
To investigate the usefulness of thyroglobulin mRNA (Tg-mRNA) detection in peripheral blood in the follow-up of papillary and follicular (differentiated) thyroid cancer, a literature study was performed. Both evidence for and evidence against the usefulness of Tg-mRNA detection were found. Also, evidence for the expression of Tg-mRNA in cells other than normal or neoplastic thyroid follicular cells was found. It is concluded that currently Tg-mRNA detection is not a useful tool in the follow-up of differentiated thyroid carcinoma, but that the concept of using RT-PCR measurements during follow-up still warrants further research.
Original language | English |
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Pages (from-to) | 200-204 |
Number of pages | 5 |
Journal | British Journal of Cancer |
Volume | 91 |
Issue number | 2 |
DOIs | |
Publication status | Published - 2004 |
Keywords
- Econometric and Statistical Methods: General
- Geneeskunde(GENK)
- Bescherming en bevordering van de menselijke gezondheid
- Other medical specialities