Detecting "different": Pyrin senses modified GTPases

Marcel R de Zoete; Richard A Flavell

doi:10.1038/cr.2014.101

Detecting "different": Pyrin senses modified GTPases

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Pathogenic bacteria secrete effector proteins that target host cell Rho GTPases to manipulate the actin cytoskeleton. A recent study in Nature identifies the Pyrin inflammasome as a sensor of this pathogenic process.

Original language	English
Pages (from-to)	1286-7
Number of pages	2
Journal	Cell Research
Volume	24
Issue number	11
DOIs	https://doi.org/10.1038/cr.2014.101
Publication status	Published - Nov 2014
Externally published	Yes

Keywords

Animals
Cytoskeletal Proteins/metabolism
Humans
Immunity, Innate/immunology
Inflammasomes/metabolism
rho GTP-Binding Proteins/metabolism

Access to Document

10.1038/cr.2014.101

Cite this

@article{c064b0b9ab1f44dc97616127786cfd6d,

title = "Detecting {"}different{"}: Pyrin senses modified GTPases",

abstract = "Pathogenic bacteria secrete effector proteins that target host cell Rho GTPases to manipulate the actin cytoskeleton. A recent study in Nature identifies the Pyrin inflammasome as a sensor of this pathogenic process. ",

keywords = "Animals, Cytoskeletal Proteins/metabolism, Humans, Immunity, Innate/immunology, Inflammasomes/metabolism, rho GTP-Binding Proteins/metabolism",

author = "\{de Zoete\}, \{Marcel R\} and Flavell, \{Richard A\}",

year = "2014",

month = nov,

doi = "10.1038/cr.2014.101",

language = "English",

volume = "24",

pages = "1286--7",

journal = "Cell Research",

issn = "1001-0602",

publisher = "Springer Nature",

number = "11",

}

TY - JOUR

T1 - Detecting "different"

T2 - Pyrin senses modified GTPases

AU - de Zoete, Marcel R

AU - Flavell, Richard A

PY - 2014/11

Y1 - 2014/11

N2 - Pathogenic bacteria secrete effector proteins that target host cell Rho GTPases to manipulate the actin cytoskeleton. A recent study in Nature identifies the Pyrin inflammasome as a sensor of this pathogenic process.

AB - Pathogenic bacteria secrete effector proteins that target host cell Rho GTPases to manipulate the actin cytoskeleton. A recent study in Nature identifies the Pyrin inflammasome as a sensor of this pathogenic process.

KW - Animals

KW - Cytoskeletal Proteins/metabolism

KW - Humans

KW - Immunity, Innate/immunology

KW - Inflammasomes/metabolism

KW - rho GTP-Binding Proteins/metabolism

U2 - 10.1038/cr.2014.101

DO - 10.1038/cr.2014.101

M3 - Article

C2 - 25091449

SN - 1001-0602

VL - 24

SP - 1286

EP - 1287

JO - Cell Research

JF - Cell Research

IS - 11

ER -

Detecting "different": Pyrin senses modified GTPases

Abstract

Keywords

Access to Document

Fingerprint

Cite this