TY - JOUR
T1 - Design of the ZWOT-CASE study
T2 - An observational study on the effectiveness of an integrated programme for cardiovascular risk management compared to usual care in general practice
AU - Marchal, Suzanne
AU - Hollander, Monika
AU - Schoenmakers, Marieke
AU - Schouwink, Michiel
AU - Timmer, Jorik R.
AU - Bilo, Henk J.G.
AU - Schwantje, Olof
AU - Van 'T Hof, Arnoud W.J.
AU - Hoes, Arno W.
N1 - Funding Information:
The study is supported by Hein Hogerzeil Foundation and Isala hospital Zwolle, the Netherlands. Both funding sources have had no influence on the design of the protocol.
Funding Information:
The study was reviewed by the Isala hospital Review Board and exempted from full assessment under the Medical Research Involving Human Subjects Act on the 16th of June 2016 (reference number 16.06104).
Publisher Copyright:
© 2019 The Author(s).
PY - 2019/11/1
Y1 - 2019/11/1
N2 - Background: Cardiovascular diseases (CVD) contribute considerably to mortality and morbidity. Prevention of CVD by lifestyle change and medication is important and needs full attention. In the Netherlands an integrated programme for cardiovascular risk management (CVRM), based on the Chronic Care Model (CCM), has been introduced in primary care in many regions in recent years, but its effects are unknown. In the ZWOT-CASE study we will assess the effect of integrated care for CVRM in the region of Zwolle on two major cardiovascular risk factors: systolic blood pressure (SBP) and low-density lipoprotein cholesterol (LDL-cholesterol) in patients with or at high risk of CVD. Methods: This study is a pragmatic observational study comparing integrated care for CVRM with usual care among patients aged 40-80 years with CVD (n = 370) or with a high CVD risk (n = 370) within 26 general practices. After 1 yr follow-up, primary outcomes (SBP and LDL-cholesterol level) are measured. Secondary outcomes include lifestyle habits (smoking, dietary habits, alcohol use, physical activity), risk factor awareness, 10-year risk of cardiovascular morbidity or mortality, health care consumption, patient satisfaction and quality of life. Conclusion: The ZWOT-CASE study will provide insight in the effects of integrated care for CVRM in general practice in patients with CVD or at high CVD risk. Trial registration: The ZWOlle Transmural Integrated Care for CArdiovaScular Risk Management Study; ClinicalTrials.gov; Identifier: NCT03428061; date of registration: 09-02-2018; This study has been retrospectively registered.
AB - Background: Cardiovascular diseases (CVD) contribute considerably to mortality and morbidity. Prevention of CVD by lifestyle change and medication is important and needs full attention. In the Netherlands an integrated programme for cardiovascular risk management (CVRM), based on the Chronic Care Model (CCM), has been introduced in primary care in many regions in recent years, but its effects are unknown. In the ZWOT-CASE study we will assess the effect of integrated care for CVRM in the region of Zwolle on two major cardiovascular risk factors: systolic blood pressure (SBP) and low-density lipoprotein cholesterol (LDL-cholesterol) in patients with or at high risk of CVD. Methods: This study is a pragmatic observational study comparing integrated care for CVRM with usual care among patients aged 40-80 years with CVD (n = 370) or with a high CVD risk (n = 370) within 26 general practices. After 1 yr follow-up, primary outcomes (SBP and LDL-cholesterol level) are measured. Secondary outcomes include lifestyle habits (smoking, dietary habits, alcohol use, physical activity), risk factor awareness, 10-year risk of cardiovascular morbidity or mortality, health care consumption, patient satisfaction and quality of life. Conclusion: The ZWOT-CASE study will provide insight in the effects of integrated care for CVRM in general practice in patients with CVD or at high CVD risk. Trial registration: The ZWOlle Transmural Integrated Care for CArdiovaScular Risk Management Study; ClinicalTrials.gov; Identifier: NCT03428061; date of registration: 09-02-2018; This study has been retrospectively registered.
KW - Cardiovascular disease
KW - Integrated care/ disease management programme
KW - Prevention
KW - Primary care
UR - http://www.scopus.com/inward/record.url?scp=85074414645&partnerID=8YFLogxK
U2 - 10.1186/s12875-019-1039-z
DO - 10.1186/s12875-019-1039-z
M3 - Article
C2 - 31675925
AN - SCOPUS:85074414645
SN - 1471-2296
VL - 20
JO - BMC Family Practice
JF - BMC Family Practice
IS - 1
M1 - 149
ER -