Dendritic cells, Fc{gamma} receptors, and Toll-like receptors: potential allies in the battle against rheumatoid arthritis

T R D J Radstake, A W T van Lieshout, P L C M van Riel, W B van den Berg, G J Adema

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Recent findings suggest an important role for Fcgamma receptors and Toll-like receptors expressed by dendritic cells (DC) in the pathogenesis of rheumatoid arthritis (RA). Possibly, DC behaviour might be tuned to counteract the misbalanced immune system in RA. Understanding the precise mechanisms that determine the skewed immune response in RA may provide new clues for the therapeutic use of DC in RA.

Original languageEnglish
Pages (from-to)1532-8
Number of pages7
JournalAnnals of the Rheumatic Diseases
Volume64
Issue number11
DOIs
Publication statusPublished - Nov 2005
Externally publishedYes

Keywords

  • Arthritis, Rheumatoid
  • Dendritic Cells
  • Humans
  • Immune Tolerance
  • Receptors, IgG
  • Synovitis
  • Toll-Like Receptors
  • Journal Article
  • Review

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