Demonstration of motion-compensated volumetric modulated arc radiotherapy on an MR-linac

Pim T.S. Borman; Prescilla Uijtewaal; Jeffrey Snyder; Bryan Allen; Caiden K. Atienza; Peter Woodhead; Daniel E. Hyer; Bas W. Raaymakers; Martin F. Fast

doi:10.1016/j.phro.2025.100729

Demonstration of motion-compensated volumetric modulated arc radiotherapy on an MR-linac

Pim T.S. Borman^*, Prescilla Uijtewaal, Jeffrey Snyder, Bryan Allen, Caiden K. Atienza, Peter Woodhead, Daniel E. Hyer, Bas W. Raaymakers, Martin F. Fast

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Intensity-modulated radiotherapy (IMRT) in combination with magnetic resonance imaging (MRI)-guided gated delivery represents the latest development in the treatment of abdominothoracic tumours on MR-linac. In contrast, volumetric-modulated arc therapy (VMAT) is typically used on conventional linacs due to its superior delivery efficiency and speed. Non-inferior VMAT plans were created in a research treatment planning system for eight lung cancer patients previously treated on an MR-linac. VMAT plans were delivered on a moving dosimeter using respiratory multi-leaf collimator (MLC) tracking. VMAT with MLC tracking achieved an average 2%/2 mm local gamma pass rate of 93% relative to planned dose with a delivery efficiency of 83%.

Original language	English
Article number	100729
Journal	Physics and Imaging in Radiation Oncology
Volume	33
DOIs	https://doi.org/10.1016/j.phro.2025.100729
Publication status	Published - Jan 2025

Keywords

Lung cancer
MLC tracking
MR-linac
VMAT

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PIIS240563162500034XFinal published version, 840 KBLicence: CC BY

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title = "Demonstration of motion-compensated volumetric modulated arc radiotherapy on an MR-linac",

abstract = "Intensity-modulated radiotherapy (IMRT) in combination with magnetic resonance imaging (MRI)-guided gated delivery represents the latest development in the treatment of abdominothoracic tumours on MR-linac. In contrast, volumetric-modulated arc therapy (VMAT) is typically used on conventional linacs due to its superior delivery efficiency and speed. Non-inferior VMAT plans were created in a research treatment planning system for eight lung cancer patients previously treated on an MR-linac. VMAT plans were delivered on a moving dosimeter using respiratory multi-leaf collimator (MLC) tracking. VMAT with MLC tracking achieved an average 2%/2 mm local gamma pass rate of 93% relative to planned dose with a delivery efficiency of 83%.",

keywords = "Lung cancer, MLC tracking, MR-linac, VMAT",

author = "Borman, {Pim T.S.} and Prescilla Uijtewaal and Jeffrey Snyder and Bryan Allen and Atienza, {Caiden K.} and Peter Woodhead and Hyer, {Daniel E.} and Raaymakers, {Bas W.} and Fast, {Martin F.}",

note = "Publisher Copyright: {\textcopyright} 2025 The Authors",

year = "2025",

month = jan,

doi = "10.1016/j.phro.2025.100729",

language = "English",

volume = "33",

journal = "Physics and Imaging in Radiation Oncology",

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T1 - Demonstration of motion-compensated volumetric modulated arc radiotherapy on an MR-linac

AU - Borman, Pim T.S.

AU - Uijtewaal, Prescilla

AU - Snyder, Jeffrey

AU - Allen, Bryan

AU - Atienza, Caiden K.

AU - Woodhead, Peter

AU - Hyer, Daniel E.

AU - Raaymakers, Bas W.

AU - Fast, Martin F.

PY - 2025/1

Y1 - 2025/1

N2 - Intensity-modulated radiotherapy (IMRT) in combination with magnetic resonance imaging (MRI)-guided gated delivery represents the latest development in the treatment of abdominothoracic tumours on MR-linac. In contrast, volumetric-modulated arc therapy (VMAT) is typically used on conventional linacs due to its superior delivery efficiency and speed. Non-inferior VMAT plans were created in a research treatment planning system for eight lung cancer patients previously treated on an MR-linac. VMAT plans were delivered on a moving dosimeter using respiratory multi-leaf collimator (MLC) tracking. VMAT with MLC tracking achieved an average 2%/2 mm local gamma pass rate of 93% relative to planned dose with a delivery efficiency of 83%.

AB - Intensity-modulated radiotherapy (IMRT) in combination with magnetic resonance imaging (MRI)-guided gated delivery represents the latest development in the treatment of abdominothoracic tumours on MR-linac. In contrast, volumetric-modulated arc therapy (VMAT) is typically used on conventional linacs due to its superior delivery efficiency and speed. Non-inferior VMAT plans were created in a research treatment planning system for eight lung cancer patients previously treated on an MR-linac. VMAT plans were delivered on a moving dosimeter using respiratory multi-leaf collimator (MLC) tracking. VMAT with MLC tracking achieved an average 2%/2 mm local gamma pass rate of 93% relative to planned dose with a delivery efficiency of 83%.

KW - Lung cancer

KW - MLC tracking

KW - MR-linac

KW - VMAT

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U2 - 10.1016/j.phro.2025.100729

DO - 10.1016/j.phro.2025.100729

M3 - Article

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SN - 2405-6316

VL - 33

JO - Physics and Imaging in Radiation Oncology

JF - Physics and Imaging in Radiation Oncology

M1 - 100729

ER -

Demonstration of motion-compensated volumetric modulated arc radiotherapy on an MR-linac

Abstract

Keywords

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