Abstract
Auto-encoders and their variational counterparts form a family of (deep) neural networks that serve a wide range of applications in medical research and clinical practice. In this chapter we provide a comprehensive overview of how auto-encoders work and how they can be used to improve medical research. We elaborate on various topics such as dimension reduction, denoising auto-encoders, auto-encoders used for anomaly detection and the applications of representations of data created using auto-encoders. Secondly, we touch upon the subject of variational auto-encoders, explaining their design and training process. We end the chapter with small scale examples of auto-encoders applied to the MNIST dataset and a recent example of an application of a (disentangled) variational auto-encoder applied to ECG-data.
| Original language | English |
|---|---|
| Title of host publication | Clinical Applications of Artificial Intelligence in Real-World Data |
| Editors | Folkert W. Asselbergs, Spiros Denaxas, Daniel L. Oberski, Jason H. Moore |
| Publisher | Springer |
| Pages | 203-220 |
| Number of pages | 18 |
| Edition | 1 |
| ISBN (Electronic) | 9783031366789 |
| ISBN (Print) | 9783031366772 |
| DOIs | |
| Publication status | Published - 5 Nov 2023 |
Keywords
- Anomaly detection
- Auto-encoder
- Deep learning
- Denoising
- Dimension reduction
- Disentanglement
- ECG
- Explainable AI
- Variational auto-encoder