De rol van neonataal kernspinresonantieonderzoek bij het voorspellen van de ontwikkeling van voldragen kinderen met perinatale asfyxie

The role of magnetic resonance imaging (MRI) in the prediction of subsequent naurodevelopmental outcome was evaluated in 100 fullterm infants with perinatal asphyxia. MRI was performed in all surviving infants within the first 2 weeks of life. MRI was not always available in those who died, but in these infants a postmortem was available. Seventy-three infants survived and were seen in the follow-up clinic for at least 18 months. Of them. 26 developed cerebral palsy. All 20 infants with normal MRI were normal at (early) follow-up. The risk of an abnormal outcome was greatest in those with severe lesions in the basal ganglia involving abnormal signal intensity of the posterior limb of the internal capsule. Cystic lesions in the white matter also carried a high risk for a poor outcome. MRI plays an important role in the assessment of the fullterm infant with perinatal asphyxia.