De Novo Genome Assembly and Comparative Genome Analysis of the Novel Human Fungal Pathogen Trichosporon austroamericanum Type-Strain CBS 17435

Elaine C Francisco; Marie Desnos-Ollivier; Bert Gerrits van den Ende; Ferry Hagen

doi:10.1007/s11046-025-00942-w

De Novo Genome Assembly and Comparative Genome Analysis of the Novel Human Fungal Pathogen Trichosporon austroamericanum Type-Strain CBS 17435

Elaine C Francisco
, Marie Desnos-Ollivier
, Bert Gerrits van den Ende
, Ferry Hagen^*

^*Corresponding author for this work

Department of Medical Microbiology

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

Trichosporon austroamericanum is a recently described species recognized for its emerging clinical significance in invasive trichosporonosis. In this study, we present the nanopore long-read-based de novo genome assembly of the type-strain CBS 17435. Additionally, we performed genomic comparative analyses with its closest relative, Trichosporon inkin.

Original language	English
Article number	33
Number of pages	1
Journal	Mycopathologia
Volume	190
Issue number	2
DOIs	https://doi.org/10.1007/s11046-025-00942-w
Publication status	Published - 4 Apr 2025

Keywords

DNA, Fungal/genetics
Genome, Fungal
Humans
Nanopore Sequencing
Phylogeny
Sequence Analysis, DNA
Trichosporon/genetics
Trichosporonosis/microbiology

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title = "De Novo Genome Assembly and Comparative Genome Analysis of the Novel Human Fungal Pathogen Trichosporon austroamericanum Type-Strain CBS 17435",

abstract = "Trichosporon austroamericanum is a recently described species recognized for its emerging clinical significance in invasive trichosporonosis. In this study, we present the nanopore long-read-based de novo genome assembly of the type-strain CBS 17435. Additionally, we performed genomic comparative analyses with its closest relative, Trichosporon inkin.",

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AU - Francisco, Elaine C

AU - Desnos-Ollivier, Marie

AU - Gerrits van den Ende, Bert

AU - Hagen, Ferry

N1 - Publisher Copyright: © The Author(s) 2025.

PY - 2025/4/4

Y1 - 2025/4/4

N2 - Trichosporon austroamericanum is a recently described species recognized for its emerging clinical significance in invasive trichosporonosis. In this study, we present the nanopore long-read-based de novo genome assembly of the type-strain CBS 17435. Additionally, we performed genomic comparative analyses with its closest relative, Trichosporon inkin.

AB - Trichosporon austroamericanum is a recently described species recognized for its emerging clinical significance in invasive trichosporonosis. In this study, we present the nanopore long-read-based de novo genome assembly of the type-strain CBS 17435. Additionally, we performed genomic comparative analyses with its closest relative, Trichosporon inkin.

KW - DNA, Fungal/genetics

KW - Genome, Fungal

KW - Humans

KW - Nanopore Sequencing

KW - Phylogeny

KW - Sequence Analysis, DNA

KW - Trichosporon/genetics

KW - Trichosporonosis/microbiology

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DO - 10.1007/s11046-025-00942-w

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VL - 190

JO - Mycopathologia

JF - Mycopathologia

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M1 - 33

ER -

De Novo Genome Assembly and Comparative Genome Analysis of the Novel Human Fungal Pathogen Trichosporon austroamericanum Type-Strain CBS 17435

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Keywords

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