De invloed van RAAS-remmers op de endotheelfunctie. Een pluspunt voor de ACE-remmers

Translated title of the contribution: Advantage ACE inhibitors. The effect of RAAS inhibitors on endothelial function

A. Huisman*, H. A.M. Voorbij

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Atherosclerosis is accompanied by endothelial dysfunction. Nitric oxide, produced by the endothelial cell, has an antiatherogenic and antithrombotic effect. ACE inhibitors have, by limiting the degradation of bradykinin, a beneficial effect on the production of nitric oxide. It has been suggested from the outcomes of the TREND and SAVE studies that ACE inhibitors may have an antithrombotic and antiatherogenic effect. Angiotensin II antagonists possibly lack this beneficial effect of ACE inhibitors.

Translated title of the contributionAdvantage ACE inhibitors. The effect of RAAS inhibitors on endothelial function
Original languageDutch
Pages (from-to)906-910
Number of pages5
JournalPharmaceutisch Weekblad
Volume135
Issue number25
Publication statusPublished - 23 Jun 2000

Keywords

  • Angiotensin II antagonists
  • Angiotensin-converting enzyme inhibitors
  • Atherosclerosis
  • Endothelium
  • Nitric oxide

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