Cytogenetics of a case of eccrine spiradenoma

T Dijkhuizen; E van den Berg; P G Nikkels; H J Hoekstra; B de Jong

Cytogenetics of a case of eccrine spiradenoma

T Dijkhuizen
, E van den Berg
, P G Nikkels
, H J Hoekstra
, B de Jong

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

A cytogenetic study of an eccrine spiradenoma and two lymph node metastases, with a growth pattern and microscopic appearance typical for benign eccrine spiradenoma, revealed a 46,XY-5,del(16)(q22),+mar(t(?;5)(?::5q13----5qter)) karyotype. The finding of the same abnormal karyotype in the tumor and the metastases suggests a relationship between the chromosomal abnormalities and the clinical malignant behavior of this morphologic benign tumor.

Original language	English
Pages (from-to)	1085-7
Number of pages	3
Journal	Human Pathology
Volume	23
Issue number	9
Publication status	Published - Sept 1992

Keywords

Adenoma, Sweat Gland
Aged
Chromosome Aberrations
Chromosome Disorders
Humans
Karyotyping
Lymphatic Metastasis
Male
Metaphase
Thoracic Neoplasms

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title = "Cytogenetics of a case of eccrine spiradenoma",

abstract = "A cytogenetic study of an eccrine spiradenoma and two lymph node metastases, with a growth pattern and microscopic appearance typical for benign eccrine spiradenoma, revealed a 46,XY-5,del(16)(q22),+mar(t(?;5)(?::5q13----5qter)) karyotype. The finding of the same abnormal karyotype in the tumor and the metastases suggests a relationship between the chromosomal abnormalities and the clinical malignant behavior of this morphologic benign tumor.",

keywords = "Adenoma, Sweat Gland, Aged, Chromosome Aberrations, Chromosome Disorders, Humans, Karyotyping, Lymphatic Metastasis, Male, Metaphase, Thoracic Neoplasms",

author = "T Dijkhuizen and \{van den Berg\}, E and Nikkels, \{P G\} and Hoekstra, \{H J\} and \{de Jong\}, B",

year = "1992",

month = sep,

language = "English",

volume = "23",

pages = "1085--7",

journal = "Human Pathology",

issn = "0046-8177",

publisher = "W.B. Saunders",

number = "9",

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TY - JOUR

T1 - Cytogenetics of a case of eccrine spiradenoma

AU - Dijkhuizen, T

AU - van den Berg, E

AU - Nikkels, P G

AU - Hoekstra, H J

AU - de Jong, B

PY - 1992/9

Y1 - 1992/9

N2 - A cytogenetic study of an eccrine spiradenoma and two lymph node metastases, with a growth pattern and microscopic appearance typical for benign eccrine spiradenoma, revealed a 46,XY-5,del(16)(q22),+mar(t(?;5)(?::5q13----5qter)) karyotype. The finding of the same abnormal karyotype in the tumor and the metastases suggests a relationship between the chromosomal abnormalities and the clinical malignant behavior of this morphologic benign tumor.

AB - A cytogenetic study of an eccrine spiradenoma and two lymph node metastases, with a growth pattern and microscopic appearance typical for benign eccrine spiradenoma, revealed a 46,XY-5,del(16)(q22),+mar(t(?;5)(?::5q13----5qter)) karyotype. The finding of the same abnormal karyotype in the tumor and the metastases suggests a relationship between the chromosomal abnormalities and the clinical malignant behavior of this morphologic benign tumor.

KW - Adenoma, Sweat Gland

KW - Aged

KW - Chromosome Aberrations

KW - Chromosome Disorders

KW - Humans

KW - Karyotyping

KW - Lymphatic Metastasis

KW - Male

KW - Metaphase

KW - Thoracic Neoplasms

M3 - Article

C2 - 1325410

SN - 0046-8177

VL - 23

SP - 1085

EP - 1087

JO - Human Pathology

JF - Human Pathology

IS - 9

ER -

Cytogenetics of a case of eccrine spiradenoma

Abstract

Keywords

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