CT-angiography source images indicate less fatal outcome despite coma of patients in the Basilar Artery International Cooperation Study

Lars P. Pallesen; Andrei Khomenko; Imanuel Dzialowski; Jessica Barlinn; Kristian Barlinn; Charlotte Zerna; Erik J R J van der Hoeven; Ale Algra; L. Jaap Kapelle; Patrik Michel; Ulf Bodechtel; Andrew M. Demchuk; Wouter Schonewille; Volker Puetz

doi:10.1177/1747493016669886

CT-angiography source images indicate less fatal outcome despite coma of patients in the Basilar Artery International Cooperation Study

Lars P. Pallesen^*, Andrei Khomenko, Imanuel Dzialowski, Jessica Barlinn, Kristian Barlinn, Charlotte Zerna, Erik J R J van der Hoeven, Ale Algra, L. Jaap Kapelle, Patrik Michel, Ulf Bodechtel, Andrew M. Demchuk, Wouter Schonewille, Volker Puetz

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Background: Coma is associated with poor outcome in patients with basilar artery occlusion. Aims: We sought to assess whether the posterior circulation Acute Stroke Prognosis Early CT Score and the Pons-Midbrain Index applied to CT angiography source images predict the outcome of comatose patients in the Basilar Artery International Cooperation Study. Methods: Basilar Artery International Cooperation Study was a prospective, observational registry of patients with acute basilar artery occlusion with 48 recruiting centers worldwide. We applied posterior circulation Acute Stroke Prognosis Early CT Score and Pons-Midbrain Index to CT angiography source images of Basilar Artery International Cooperation Study patients who presented with coma. We calculated adjusted risk ratios to assess the association of dichotomized posterior circulation Acute Stroke Prognosis Early CT Score (≥8 vs.

Original language	English
Pages (from-to)	145-151
Number of pages	7
Journal	International Journal of Stroke
Volume	12
Issue number	2
DOIs	https://doi.org/10.1177/1747493016669886
Publication status	Published - 2017

Keywords

Basilar artery occlusion
coma
CTA source images
imaging scores
ischemic stroke
thrombolysis
Review

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10.1177/1747493016669886

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Pallesen, L. P., Khomenko, A., Dzialowski, I., Barlinn, J., Barlinn, K., Zerna, C., van der Hoeven, E. J. R. J., Algra, A., Kapelle, L. J., Michel, P., Bodechtel, U., Demchuk, A. M., Schonewille, W., & Puetz, V. (2017). CT-angiography source images indicate less fatal outcome despite coma of patients in the Basilar Artery International Cooperation Study. International Journal of Stroke, 12(2), 145-151. https://doi.org/10.1177/1747493016669886

@article{37c4da6bb32a42d080c1d2a482bb42a0,

title = "CT-angiography source images indicate less fatal outcome despite coma of patients in the Basilar Artery International Cooperation Study",

abstract = "Background: Coma is associated with poor outcome in patients with basilar artery occlusion. Aims: We sought to assess whether the posterior circulation Acute Stroke Prognosis Early CT Score and the Pons-Midbrain Index applied to CT angiography source images predict the outcome of comatose patients in the Basilar Artery International Cooperation Study. Methods: Basilar Artery International Cooperation Study was a prospective, observational registry of patients with acute basilar artery occlusion with 48 recruiting centers worldwide. We applied posterior circulation Acute Stroke Prognosis Early CT Score and Pons-Midbrain Index to CT angiography source images of Basilar Artery International Cooperation Study patients who presented with coma. We calculated adjusted risk ratios to assess the association of dichotomized posterior circulation Acute Stroke Prognosis Early CT Score (≥8 vs. ",

keywords = "Basilar artery occlusion, coma, CTA source images, imaging scores, ischemic stroke, thrombolysis, Review",

author = "Pallesen, {Lars P.} and Andrei Khomenko and Imanuel Dzialowski and Jessica Barlinn and Kristian Barlinn and Charlotte Zerna and {van der Hoeven}, {Erik J R J} and Ale Algra and Kapelle, {L. Jaap} and Patrik Michel and Ulf Bodechtel and Demchuk, {Andrew M.} and Wouter Schonewille and Volker Puetz",

year = "2017",

doi = "10.1177/1747493016669886",

language = "English",

volume = "12",

pages = "145--151",

journal = "International Journal of Stroke",

issn = "1747-4930",

publisher = "Blackwell Publishing Asia Pty Ltd",

number = "2",

}

Pallesen, LP, Khomenko, A, Dzialowski, I, Barlinn, J, Barlinn, K, Zerna, C, van der Hoeven, EJRJ, Algra, A , Kapelle, LJ, Michel, P, Bodechtel, U, Demchuk, AM, Schonewille, W & Puetz, V 2017, 'CT-angiography source images indicate less fatal outcome despite coma of patients in the Basilar Artery International Cooperation Study', International Journal of Stroke, vol. 12, no. 2, pp. 145-151. https://doi.org/10.1177/1747493016669886

TY - JOUR

T1 - CT-angiography source images indicate less fatal outcome despite coma of patients in the Basilar Artery International Cooperation Study

AU - Pallesen, Lars P.

AU - Khomenko, Andrei

AU - Dzialowski, Imanuel

AU - Barlinn, Jessica

AU - Barlinn, Kristian

AU - Zerna, Charlotte

AU - van der Hoeven, Erik J R J

AU - Algra, Ale

AU - Kapelle, L. Jaap

AU - Michel, Patrik

AU - Bodechtel, Ulf

AU - Demchuk, Andrew M.

AU - Schonewille, Wouter

AU - Puetz, Volker

PY - 2017

Y1 - 2017

N2 - Background: Coma is associated with poor outcome in patients with basilar artery occlusion. Aims: We sought to assess whether the posterior circulation Acute Stroke Prognosis Early CT Score and the Pons-Midbrain Index applied to CT angiography source images predict the outcome of comatose patients in the Basilar Artery International Cooperation Study. Methods: Basilar Artery International Cooperation Study was a prospective, observational registry of patients with acute basilar artery occlusion with 48 recruiting centers worldwide. We applied posterior circulation Acute Stroke Prognosis Early CT Score and Pons-Midbrain Index to CT angiography source images of Basilar Artery International Cooperation Study patients who presented with coma. We calculated adjusted risk ratios to assess the association of dichotomized posterior circulation Acute Stroke Prognosis Early CT Score (≥8 vs.

AB - Background: Coma is associated with poor outcome in patients with basilar artery occlusion. Aims: We sought to assess whether the posterior circulation Acute Stroke Prognosis Early CT Score and the Pons-Midbrain Index applied to CT angiography source images predict the outcome of comatose patients in the Basilar Artery International Cooperation Study. Methods: Basilar Artery International Cooperation Study was a prospective, observational registry of patients with acute basilar artery occlusion with 48 recruiting centers worldwide. We applied posterior circulation Acute Stroke Prognosis Early CT Score and Pons-Midbrain Index to CT angiography source images of Basilar Artery International Cooperation Study patients who presented with coma. We calculated adjusted risk ratios to assess the association of dichotomized posterior circulation Acute Stroke Prognosis Early CT Score (≥8 vs.

KW - Basilar artery occlusion

KW - coma

KW - CTA source images

KW - imaging scores

KW - ischemic stroke

KW - thrombolysis

KW - Review

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DO - 10.1177/1747493016669886

M3 - Article

C2 - 27698280

AN - SCOPUS:85011545476

SN - 1747-4930

VL - 12

SP - 145

EP - 151

JO - International Journal of Stroke

JF - International Journal of Stroke

IS - 2

ER -

CT-angiography source images indicate less fatal outcome despite coma of patients in the Basilar Artery International Cooperation Study

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