Cryptococcus gattii infection in an immunocompetent patient from Southern Italy

  • Roberta Iatta*
  • , Ferry Hagen
  • , Cecilia Fico
  • , Nunzia Lopatriello
  • , Teun Boekhout
  • , Maria Teresa Montagna
  • *Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Cryptococcus gattii has becoming more prevalent in temperate climate zones, during the past decades. We describe a C. gattii serotype B infection in an immunocompetent Italian patient with sclerosing cholangitis. The patient traveled once to Eastern Canada and otherwise no other countries than Italy were visited. Molecular analysis revealed that the C. gattii isolate belong to genotype AFLP4/VGI and has mating-type α which is the most common genotype in the Mediterranean environment. The C. gattii strain was found to be closely related, but not identical, to other C. gattii strains from the Mediterranean area.

Original languageEnglish
Pages (from-to)87-92
Number of pages6
JournalMycopathologia
Volume174
Issue number1
DOIs
Publication statusPublished - Jul 2012
Externally publishedYes

Keywords

  • Adult
  • Amplified Fragment Length Polymorphism Analysis
  • Cholangitis, Sclerosing/complications
  • Cluster Analysis
  • Cryptococcosis/diagnosis
  • Cryptococcus gattii/isolation & purification
  • Genes, Mating Type, Fungal
  • Humans
  • Italy
  • Male
  • Molecular Typing
  • Mycological Typing Techniques
  • Phylogeny
  • Radiography, Thoracic
  • Serotyping
  • Tomography, X-Ray Computed

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