Cryptococcal Meningitis Presenting as a Complication in HIV-infected Children: A Case Series From Sub-Saharan Africa

Tinashe K Nyazika; Faith Masanganise; Ferry Hagen; Mutsawashe F Bwakura-Dangarembizi; Ismail M H Ticklay; Valerie J Robertson

doi:10.1097/INF.0000000000001212

Cryptococcal Meningitis Presenting as a Complication in HIV-infected Children: A Case Series From Sub-Saharan Africa

Tinashe K Nyazika^*
, Faith Masanganise
, Ferry Hagen
, Mutsawashe F Bwakura-Dangarembizi
, Ismail M H Ticklay
, Valerie J Robertson

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Cryptococcal meningitis is a leading infectious disease worldwide as a result of the high burden of HIV and AIDS, although its cumulative incidence is very low in children compared with that in adults. Very few studies involving the disease in children have been reported including sub-Saharan Africa, with the highest prevalence of HIV-infected children in the world. We summarize 5 cases of children diagnosed with cryptococcal meningitis at a tertiary hospital in Harare, Zimbabwe, between October 1, 2013, and September 30, 2014.

Original language	English
Pages (from-to)	979-80
Number of pages	2
Journal	The Pediatric infectious disease journal
Volume	35
Issue number	9
DOIs	https://doi.org/10.1097/INF.0000000000001212
Publication status	Published - Sept 2016
Externally published	Yes

Keywords

AIDS-Related Opportunistic Infections/diagnosis
Adolescent
Africa South of the Sahara
Anti-Retroviral Agents/therapeutic use
Child
HIV Infections/complications
Humans
Male
Meningitis, Cryptococcal/diagnosis
Retrospective Studies

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title = "Cryptococcal Meningitis Presenting as a Complication in HIV-infected Children: A Case Series From Sub-Saharan Africa",

abstract = "Cryptococcal meningitis is a leading infectious disease worldwide as a result of the high burden of HIV and AIDS, although its cumulative incidence is very low in children compared with that in adults. Very few studies involving the disease in children have been reported including sub-Saharan Africa, with the highest prevalence of HIV-infected children in the world. We summarize 5 cases of children diagnosed with cryptococcal meningitis at a tertiary hospital in Harare, Zimbabwe, between October 1, 2013, and September 30, 2014.",

keywords = "AIDS-Related Opportunistic Infections/diagnosis, Adolescent, Africa South of the Sahara, Anti-Retroviral Agents/therapeutic use, Child, HIV Infections/complications, Humans, Male, Meningitis, Cryptococcal/diagnosis, Retrospective Studies",

author = "Nyazika, \{Tinashe K\} and Faith Masanganise and Ferry Hagen and Bwakura-Dangarembizi, \{Mutsawashe F\} and Ticklay, \{Ismail M H\} and Robertson, \{Valerie J\}",

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doi = "10.1097/INF.0000000000001212",

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volume = "35",

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AU - Nyazika, Tinashe K

AU - Masanganise, Faith

AU - Hagen, Ferry

AU - Bwakura-Dangarembizi, Mutsawashe F

AU - Ticklay, Ismail M H

AU - Robertson, Valerie J

PY - 2016/9

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AB - Cryptococcal meningitis is a leading infectious disease worldwide as a result of the high burden of HIV and AIDS, although its cumulative incidence is very low in children compared with that in adults. Very few studies involving the disease in children have been reported including sub-Saharan Africa, with the highest prevalence of HIV-infected children in the world. We summarize 5 cases of children diagnosed with cryptococcal meningitis at a tertiary hospital in Harare, Zimbabwe, between October 1, 2013, and September 30, 2014.

KW - AIDS-Related Opportunistic Infections/diagnosis

KW - Adolescent

KW - Africa South of the Sahara

KW - Anti-Retroviral Agents/therapeutic use

KW - Child

KW - HIV Infections/complications

KW - Humans

KW - Male

KW - Meningitis, Cryptococcal/diagnosis

KW - Retrospective Studies

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SN - 0891-3668

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SP - 979

EP - 980

JO - The Pediatric infectious disease journal

JF - The Pediatric infectious disease journal

IS - 9

ER -

Cryptococcal Meningitis Presenting as a Complication in HIV-infected Children: A Case Series From Sub-Saharan Africa

Abstract

Keywords

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