Crisping up Lactobacillus vaginal live biotherapeutics

Janneke H H M van de Wijgert

doi:10.1016/j.chom.2026.03.014

Crisping up Lactobacillus vaginal live biotherapeutics

Janneke H H M van de Wijgert^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Bacterial vaginosis remains prevalent and often refractory or recurrent. In this issue, Bloom et al. and Potloane et al. report clinical trial results evaluating three vaginal live biotherapeutic products containing different Lactobacillus crispatus strain combinations. Although the colonization findings are encouraging, optimization of doses, formulations, and treatment schedules is necessary.

Original language	English
Pages (from-to)	559-561
Number of pages	3
Journal	Cell Host & Microbe
Volume	34
Issue number	4
DOIs	https://doi.org/10.1016/j.chom.2026.03.014
Publication status	Published - 8 Apr 2026

Keywords

Biological Therapy/methods
Clinical Trials as Topic
Female
Humans
Lactobacillus crispatus/growth & development
Probiotics/administration & dosage
Vagina/microbiology
Vaginosis, Bacterial/therapy

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10.1016/j.chom.2026.03.014

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Crisping up Lactobacillus vaginal live biotherapeutics
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Cite this

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title = "Crisping up Lactobacillus vaginal live biotherapeutics",

abstract = "Bacterial vaginosis remains prevalent and often refractory or recurrent. In this issue, Bloom et al. and Potloane et al. report clinical trial results evaluating three vaginal live biotherapeutic products containing different Lactobacillus crispatus strain combinations. Although the colonization findings are encouraging, optimization of doses, formulations, and treatment schedules is necessary.",

keywords = "Biological Therapy/methods, Clinical Trials as Topic, Female, Humans, Lactobacillus crispatus/growth \& development, Probiotics/administration \& dosage, Vagina/microbiology, Vaginosis, Bacterial/therapy",

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AB - Bacterial vaginosis remains prevalent and often refractory or recurrent. In this issue, Bloom et al. and Potloane et al. report clinical trial results evaluating three vaginal live biotherapeutic products containing different Lactobacillus crispatus strain combinations. Although the colonization findings are encouraging, optimization of doses, formulations, and treatment schedules is necessary.

KW - Biological Therapy/methods

KW - Clinical Trials as Topic

KW - Female

KW - Humans

KW - Lactobacillus crispatus/growth & development

KW - Probiotics/administration & dosage

KW - Vagina/microbiology

KW - Vaginosis, Bacterial/therapy

U2 - 10.1016/j.chom.2026.03.014

DO - 10.1016/j.chom.2026.03.014

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SP - 559

EP - 561

JO - Cell Host & Microbe

JF - Cell Host & Microbe

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ER -

Crisping up Lactobacillus vaginal live biotherapeutics

Abstract

Keywords

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