Creating human organs in chimaera pigs: an ethical source of immunocompatible organs?

David Shaw; Wybo Dondorp; Niels Geijsen; Guido de Wert

doi:10.1136/medethics-2014-102224

Creating human organs in chimaera pigs: an ethical source of immunocompatible organs?

David Shaw^*, Wybo Dondorp, Niels Geijsen, Guido de Wert

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

New techniques in regenerative medicine may soon enable the creation of human organs inside animals using induced pluripotent stem cells. This technology has the potential to solve the organ scarcity problem by providing a limitless source of personalised organs for transplantation, but also raises several ethical issues, particularly concerning animal welfare, the 'human features' problem and human dignity.

Original language	English
Pages (from-to)	970-974
Number of pages	5
Journal	Journal of Medical Ethics
Volume	41
Issue number	12
DOIs	https://doi.org/10.1136/medethics-2014-102224
Publication status	Published - Dec 2015

Keywords

PLURIPOTENT STEM-CELLS
GENERATION
XENOTRANSPLANTATION
MEGAKARYOCYTES
PLATELETS
PANCREAS

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10.1136/medethics-2014-102224

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title = "Creating human organs in chimaera pigs: an ethical source of immunocompatible organs?",

abstract = "New techniques in regenerative medicine may soon enable the creation of human organs inside animals using induced pluripotent stem cells. This technology has the potential to solve the organ scarcity problem by providing a limitless source of personalised organs for transplantation, but also raises several ethical issues, particularly concerning animal welfare, the 'human features' problem and human dignity.",

keywords = "PLURIPOTENT STEM-CELLS, GENERATION, XENOTRANSPLANTATION, MEGAKARYOCYTES, PLATELETS, PANCREAS",

author = "David Shaw and Wybo Dondorp and Niels Geijsen and {de Wert}, Guido",

year = "2015",

month = dec,

doi = "10.1136/medethics-2014-102224",

language = "English",

volume = "41",

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journal = "Journal of Medical Ethics",

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T2 - an ethical source of immunocompatible organs?

AU - Shaw, David

AU - Dondorp, Wybo

AU - Geijsen, Niels

AU - de Wert, Guido

PY - 2015/12

Y1 - 2015/12

N2 - New techniques in regenerative medicine may soon enable the creation of human organs inside animals using induced pluripotent stem cells. This technology has the potential to solve the organ scarcity problem by providing a limitless source of personalised organs for transplantation, but also raises several ethical issues, particularly concerning animal welfare, the 'human features' problem and human dignity.

AB - New techniques in regenerative medicine may soon enable the creation of human organs inside animals using induced pluripotent stem cells. This technology has the potential to solve the organ scarcity problem by providing a limitless source of personalised organs for transplantation, but also raises several ethical issues, particularly concerning animal welfare, the 'human features' problem and human dignity.

KW - PLURIPOTENT STEM-CELLS

KW - GENERATION

KW - XENOTRANSPLANTATION

KW - MEGAKARYOCYTES

KW - PLATELETS

KW - PANCREAS

U2 - 10.1136/medethics-2014-102224

DO - 10.1136/medethics-2014-102224

M3 - Article

C2 - 25378549

SN - 0306-6800

VL - 41

SP - 970

EP - 974

JO - Journal of Medical Ethics

JF - Journal of Medical Ethics

IS - 12

ER -

Creating human organs in chimaera pigs: an ethical source of immunocompatible organs?

Abstract

Keywords

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