Cost-effectiveness of targeted screening for hepatitis C in The Netherlands

C.W. Helsper, B. Borkent-Raven, N.J. de Wit, G.A. van Essen, M.J.M. Bonten, A.I.M. Hoepelman, M.P. Janssen, G.A. de Wit

Research output: Contribution to journalArticleAcademicpeer-review


On account of the serious complications of hepatitis C virus (HCV) infection and the improved treatment possibilities, the need to improve HCV awareness and case-finding is increasingly recognized. To optimize a future national campaign with this objective, three pilot campaigns were executed in three regions in The Netherlands. One campaign was aimed at the general population, a second (similar) campaign was extended with a support programme for primary care and a third campaign was specifically aimed at hard-drug users. Data from the pilot campaigns were used to build a mathematical model to estimate the incremental cost-effectiveness ratio of the different campaigns. The campaign aimed at the general public without support for primary care did not improve case-finding and was therefore not cost-effective. The similar campaign accompanied by additional support for primary care and the campaign aimed at hard-drug users emerged as cost-effective interventions for identification of HCV carriers.

Original languageEnglish
Pages (from-to)58-69
Number of pages12
JournalEpidemiology and Infection
Issue number1
Publication statusPublished - Jan 2012


  • Communicable Diseases, Emerging
  • Cost-Benefit Analysis
  • Drug Users
  • Health Promotion
  • Hepatitis C
  • Humans
  • Mass Screening
  • Multivariate Analysis
  • Netherlands
  • Pilot Projects


Dive into the research topics of 'Cost-effectiveness of targeted screening for hepatitis C in The Netherlands'. Together they form a unique fingerprint.

Cite this