Correction to: Lower activity of cholesteryl ester transfer protein (CETP) and the risk of dementia: a Mendelian randomization analysis (Alzheimer's Research & Therapy, (2024), 16, 1, (228), 10.1186/s13195-024-01594-6)

Amand F. Schmidt*, Michael H. Davidson, Marc Ditmarsch, John J. Kastelein, Chris Finan

*Corresponding author for this work

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

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Abstract

Correction: Alz Res Therapy 16, 228 (2024) Following publication of the original article [1], an important textual error was noticed and corrected in the fourth paragraph of Background section. The current wording erroneously states that CETP inhibitors decreases Apo-E concentration: However, all CETP inhibitors, including the novel CETP-inhibitor obicetrapib, lowers plasma concentrations of apolipoprotein-E (Apo-E) [4] which is a known risk factor for dementia, in particular for Alzheimer’s disease (AD). Whereas the cited reference [4] actually shows an increasing effect. The correct wording should read: However, all CETP inhibitors, including the novel CETP-inhibitor obicetrapib, increase plasma concentrations of apolipoprotein-E (Apo-E) [4], which is associated with decreased risk of dementia, in particular for Alzheimer’s disease (AD). The original article [1] has been updated.

Original languageEnglish
Article number276
JournalAlzheimer's Research and Therapy
Volume16
Issue number1
DOIs
Publication statusPublished - 27 Dec 2024

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