TY - JOUR
T1 - Coordinating efforts to optimize next-generation kidney replacement therapies
T2 - the European Kidney Health Alliance Work Group ‘Breakthrough Innovation’
AU - Wieringa, Fokko
AU - Søndergaard, Henning
AU - Ortiz, Alberto
N1 - Publisher Copyright:
© The Author(s) 2023.
PY - 2023/6
Y1 - 2023/6
N2 - Chronic kidney disease (CKD) is one of the fastest growing health problems, set to become the fifth global death cause by 2040. Factors contributing to this fast growth include increased survival from other diseases (cancer, cardiovascular disease, diabetes, etc.), population aging, lack of early CKD diagnosis tools, insufficient CKD awareness within healthcare systems, limited therapeutic armamentarium to prevent CKD progression and limitations of currently available kidney replacement therapies (KRTs). The European Kidney Health Alliance (EKHA) and the American Association of Kidney Patients joined forces within the Decade of the KidneyTM framework to address these issues. We report on the rationale and vision of the EKHA Work Group ‘Breakthrough Innovation’ which aims to disrupt the existing innovation paradox on KRT. We discuss how the concepts of international technological roadmapping and coopetition may leverage breakthrough KRT technologies, and present a map of the kidney innovation playing field, driven by patient advocacy groups.
AB - Chronic kidney disease (CKD) is one of the fastest growing health problems, set to become the fifth global death cause by 2040. Factors contributing to this fast growth include increased survival from other diseases (cancer, cardiovascular disease, diabetes, etc.), population aging, lack of early CKD diagnosis tools, insufficient CKD awareness within healthcare systems, limited therapeutic armamentarium to prevent CKD progression and limitations of currently available kidney replacement therapies (KRTs). The European Kidney Health Alliance (EKHA) and the American Association of Kidney Patients joined forces within the Decade of the KidneyTM framework to address these issues. We report on the rationale and vision of the EKHA Work Group ‘Breakthrough Innovation’ which aims to disrupt the existing innovation paradox on KRT. We discuss how the concepts of international technological roadmapping and coopetition may leverage breakthrough KRT technologies, and present a map of the kidney innovation playing field, driven by patient advocacy groups.
KW - chronic kidney disease (CKD)
KW - Decade of the Kidney
KW - innovation kidney failure
KW - kidney replacement therapy (KRT)
UR - http://www.scopus.com/inward/record.url?scp=85192799388&partnerID=8YFLogxK
U2 - 10.1093/ckj/sfad016
DO - 10.1093/ckj/sfad016
M3 - Review article
AN - SCOPUS:85192799388
SN - 2048-8505
VL - 16
SP - 885
EP - 890
JO - Clinical Kidney Journal
JF - Clinical Kidney Journal
IS - 6
ER -