Continuous monitoring may predict an allergic reaction during an oral food challenge: an exploratory study

E J J Kallen; T Krone; K C M Verhoeckx; A Versluis; G F Houben; S Bijlsma; W M Blom; M R O Ligeon; N A Blom; R Van Ree; A C Knulst; P M J Welsing; T M Le

doi:10.1016/j.jaip.2025.12.024

Continuous monitoring may predict an allergic reaction during an oral food challenge: an exploratory study

E J J Kallen
, T Krone
, K C M Verhoeckx
, A Versluis
, G F Houben
, S Bijlsma
, W M Blom
, M R O Ligeon
, N A Blom
, R Van Ree
, A C Knulst
, P M J Welsing
, T M Le

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Physiological parameters predicted objective allergic reactions accurately in about 60% of the food challenges, possibly enabling future earlier detection and intervention. This may help prevent severe symptoms, though larger studies are required to confirm these findings.

Original language	English
Pages (from-to)	967-969.e2
Journal	The journal of allergy and clinical immunology. In practice
Volume	14
Issue number	4
Early online date	30 Dec 2025
DOIs	https://doi.org/10.1016/j.jaip.2025.12.024
Publication status	Published - Apr 2026

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10.1016/j.jaip.2025.12.024

1-s2.0-S2213219825012395-mainFinal published version, 3.61 MBLicence: Taverne

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Kallen, E. J. J., Krone, T., Verhoeckx, K. C. M., Versluis, A., Houben, G. F., Bijlsma, S., Blom, W. M., Ligeon, M. R. O., Blom, N. A., Van Ree, R., Knulst, A. C., Welsing, P. M. J., & Le, T. M. (2026). Continuous monitoring may predict an allergic reaction during an oral food challenge: an exploratory study. The journal of allergy and clinical immunology. In practice, 14(4), 967-969.e2. https://doi.org/10.1016/j.jaip.2025.12.024

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abstract = "Physiological parameters predicted objective allergic reactions accurately in about 60\% of the food challenges, possibly enabling future earlier detection and intervention. This may help prevent severe symptoms, though larger studies are required to confirm these findings.",

author = "Kallen, \{E J J\} and T Krone and Verhoeckx, \{K C M\} and A Versluis and Houben, \{G F\} and S Bijlsma and Blom, \{W M\} and Ligeon, \{M R O\} and Blom, \{N A\} and \{Van Ree\}, R and Knulst, \{A C\} and Welsing, \{P M J\} and Le, \{T M\}",

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year = "2026",

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doi = "10.1016/j.jaip.2025.12.024",

language = "English",

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Kallen, EJJ, Krone, T, Verhoeckx, KCM, Versluis, A, Houben, GF, Bijlsma, S, Blom, WM, Ligeon, MRO, Blom, NA, Van Ree, R, Knulst, AC , Welsing, PMJ & Le, TM 2026, 'Continuous monitoring may predict an allergic reaction during an oral food challenge: an exploratory study', The journal of allergy and clinical immunology. In practice, vol. 14, no. 4, pp. 967-969.e2. https://doi.org/10.1016/j.jaip.2025.12.024

TY - JOUR

T1 - Continuous monitoring may predict an allergic reaction during an oral food challenge

T2 - an exploratory study

AU - Kallen, E J J

AU - Krone, T

AU - Verhoeckx, K C M

AU - Versluis, A

AU - Houben, G F

AU - Bijlsma, S

AU - Blom, W M

AU - Ligeon, M R O

AU - Blom, N A

AU - Van Ree, R

AU - Knulst, A C

AU - Welsing, P M J

AU - Le, T M

PY - 2026/4

Y1 - 2026/4

N2 - Physiological parameters predicted objective allergic reactions accurately in about 60% of the food challenges, possibly enabling future earlier detection and intervention. This may help prevent severe symptoms, though larger studies are required to confirm these findings.

AB - Physiological parameters predicted objective allergic reactions accurately in about 60% of the food challenges, possibly enabling future earlier detection and intervention. This may help prevent severe symptoms, though larger studies are required to confirm these findings.

UR - https://www.scopus.com/pages/publications/105029594215

U2 - 10.1016/j.jaip.2025.12.024

DO - 10.1016/j.jaip.2025.12.024

M3 - Article

C2 - 41478401

SN - 2213-2198

VL - 14

SP - 967-969.e2

JO - The journal of allergy and clinical immunology. In practice

JF - The journal of allergy and clinical immunology. In practice

IS - 4

ER -

Continuous monitoring may predict an allergic reaction during an oral food challenge: an exploratory study

Abstract

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