TY - JOUR
T1 - Contemporary assessment of short- and functional 90-days outcome in old intensive care patients suffering from COVID-19
AU - Bruno, Raphael Romano
AU - Wernly, Bernhard
AU - Artigas, Antonio
AU - Fuest, Kristina
AU - Schaller, Stefan J.
AU - Dannenberg, Lisa
AU - Kindgen-Milles, Detlef
AU - Kelm, Malte
AU - Beil, Michael
AU - Sviri, Sigal
AU - Elhadi, Muhammed
AU - Joannidis, Michael
AU - Oeyen, Sandra
AU - Kondili, Eumorfia
AU - Moreno, Rui
AU - Leaver, Susannah
AU - Guidet, Bertrand
AU - De Lange, Dylan W.
AU - Flaatten, Hans
AU - Szczeklik, Wojciech
AU - Jung, Christian
N1 - Publisher Copyright:
© 2024 The Author(s)
PY - 2025/4
Y1 - 2025/4
N2 - Purpose: There are limited data about the outcome of old intensive care (ICU) patients suffering from Covid-19 in the post-vaccination era. This study distinguishes the pre- and post-acute illness living conditions of ICU survivors from non-survivors. Methods: This prospective international multicenter study included 642 old (≥ 70 years) ICU patients, including data ranging from pre-illness condition to functional 90-days follow-up. The primary endpoint was the difference of living conditions of ICU-survivors before ICU admission and 90-days after ICU discharge. Secondary outcomes were 90-days mortality, and quality of life. Results: A total of 642 patients were included. Significantly more ICU survivors lived at their own homes without support before ICU admission than non-survivors (p = 0.016), while more non-survivors resided in nursing homes (p = 0.016). ICU mortality was 39 %, 30-days and 90 days mortality were 47 %and 55 %. After 90 days, only 22 % maintained the same living conditions. Surviving patients viewed ICU admission positively after 90 days, while relatives were more uncertain. Quality of life indicated a self-reported average score of 60 (50–75). Conclusion: Living conditions influence the outcome of critically ill old patients suffering from Covid-19. Only a minority returned to their initial habitat after ICU survival.
AB - Purpose: There are limited data about the outcome of old intensive care (ICU) patients suffering from Covid-19 in the post-vaccination era. This study distinguishes the pre- and post-acute illness living conditions of ICU survivors from non-survivors. Methods: This prospective international multicenter study included 642 old (≥ 70 years) ICU patients, including data ranging from pre-illness condition to functional 90-days follow-up. The primary endpoint was the difference of living conditions of ICU-survivors before ICU admission and 90-days after ICU discharge. Secondary outcomes were 90-days mortality, and quality of life. Results: A total of 642 patients were included. Significantly more ICU survivors lived at their own homes without support before ICU admission than non-survivors (p = 0.016), while more non-survivors resided in nursing homes (p = 0.016). ICU mortality was 39 %, 30-days and 90 days mortality were 47 %and 55 %. After 90 days, only 22 % maintained the same living conditions. Surviving patients viewed ICU admission positively after 90 days, while relatives were more uncertain. Quality of life indicated a self-reported average score of 60 (50–75). Conclusion: Living conditions influence the outcome of critically ill old patients suffering from Covid-19. Only a minority returned to their initial habitat after ICU survival.
KW - Covid-19
KW - COVIP-study
KW - Elderly
KW - Long-term outcomes
UR - http://www.scopus.com/inward/record.url?scp=85210714141&partnerID=8YFLogxK
U2 - 10.1016/j.jcrc.2024.154984
DO - 10.1016/j.jcrc.2024.154984
M3 - Article
AN - SCOPUS:85210714141
SN - 0883-9441
VL - 86
JO - Journal of Critical Care
JF - Journal of Critical Care
M1 - 154984
ER -