CONREAL web server: Identification and visualization of conserved transcription factor binding sites

Eugene Berezikov; Victor Guryev; Edwin Cuppen

doi:10.1093/nar/gki378

CONREAL web server: Identification and visualization of conserved transcription factor binding sites

Eugene Berezikov^*, Victor Guryev, Edwin Cuppen

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

18 Citations (Scopus)

Abstract

The use of orthologous sequences and phylogenetic footprinting approaches have become popular for the recognition of conserved and potentially functional sequences. Several algorithms have been developed for the identification of conserved transcription factor binding sites (TFBSs), which are characterized by their relatively short and degenerative recognition sequences. The CONREAL (conserved regulatory elements anchored alignment) web server provides a versatile interface to CONREAL-, LAGAN-, BLASTZ- and AVID-based predictions of conserved TFBSs in orthologous promoters. Comparative analysis using different algorithms can be started by keyword without any prior sequence retrieval. The interface is available at http://conreal.niob.knaw.nl.

Original language	English
Journal	Nucleic Acids Research
Volume	33
Issue number	SUPPL. 2
DOIs	https://doi.org/10.1093/nar/gki378
Publication status	Published - 1 Jul 2005

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CONREAL web server: Identification and visualization of conserved transcription factor binding sites

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