Abstract
A 34-year-old woman with a known congenital pain-insensitivity syndrome presented because of increasing weakness and sensory loss in her right leg. The cause was a rapidly progressive partial caudal compression syndrome in the absence ofknown prior trauma. Radiology revealed a lumbar Charcot spine, i.e. total destruction of the spine with compression of the dural sac. Emergency surgery included opening of the lumbar canal and spondylodesis. Postoperatively, there was almost full neurological recovery. In the pathogenesis the absence of protective pain sensation combined with trophic degeneration due to neurovascular dysregulation may play a role.
| Translated title of the contribution | Congenitaal pijnongevoeligheidssyndroom; een zeldzame aanwijzing voor het nut van pijn. |
|---|---|
| Original language | Undefined/Unknown |
| Pages (from-to) | 1527-1532 |
| Number of pages | 6 |
| Journal | Nederlands Tijdschrift voor Geneeskunde |
| Volume | 151 |
| Issue number | 27 |
| Publication status | Published - 2007 |