Component structure of the Positive And Negative Syndrome Scale (PANSS) in patients with recent-onset schizophrenia and spectrum disorders

J. E.D. Wolthaus; P. M.A.J. Dingemans; A. H. Schene; D. H. Linszen; H. Knegtering; E. A.E. Holthausen; W. Cahn; R. Hijman

doi:10.1007/s002130000459

Component structure of the Positive And Negative Syndrome Scale (PANSS) in patients with recent-onset schizophrenia and spectrum disorders

J. E.D. Wolthaus^*, P. M.A.J. Dingemans, A. H. Schene, D. H. Linszen, H. Knegtering, E. A.E. Holthausen, W. Cahn, R. Hijman

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

64 Citations (Scopus)

Abstract

Rationale: Earlier studies have examined the symptom dimensions of the PANSS (Positive And Negative Syndrome Scale) in patients with chronic schizophrenia. Results have suggested that three to eight component solutions best explain underlying symptom dimensions. Objectives: To examine the component structure of the PANSS and the MADRS (Montgomery Asberg Depression Rating Scale) in young patients with recent-onset schizophrenia and related disorders and the correlations between the components of both instruments. Methods: Symptomatology was measured in 138 patients with recent-onset schizophrenia, by administering the PANSS and the MADRS. Results: Principal component analysis of the PANSS revealed five components: a positive, negative, depression, agitation-excitement and disorganisation component. The MADRS only showed one component. A high correlation was found between the depression component of the PANSS and the overall score of the MADRS (9=0.87, P<0.001). A moderate correlation was found between the PANSS negative component and the overall score of the MADRS (p=0.51, P<0.001). Conclusions: The data suggest a five component structure of the PANSS. The depression component of the PANSS seems to be a valid way of assessing depression in patients with recent-onset schizophrenia.

Original language	English
Pages (from-to)	399-403
Number of pages	5
Journal	Psychopharmacology
Volume	150
Issue number	4
DOIs	https://doi.org/10.1007/s002130000459
Publication status	Published - 2 Aug 2000

Keywords

Component structure
Montgomery Asberg Depression Rating Scale (MADRS)
Positive And Negative Syndrome Scale (PANSS)
Psychosis
Schizophrenia

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10.1007/s002130000459

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title = "Component structure of the Positive And Negative Syndrome Scale (PANSS) in patients with recent-onset schizophrenia and spectrum disorders",

abstract = "Rationale: Earlier studies have examined the symptom dimensions of the PANSS (Positive And Negative Syndrome Scale) in patients with chronic schizophrenia. Results have suggested that three to eight component solutions best explain underlying symptom dimensions. Objectives: To examine the component structure of the PANSS and the MADRS (Montgomery Asberg Depression Rating Scale) in young patients with recent-onset schizophrenia and related disorders and the correlations between the components of both instruments. Methods: Symptomatology was measured in 138 patients with recent-onset schizophrenia, by administering the PANSS and the MADRS. Results: Principal component analysis of the PANSS revealed five components: a positive, negative, depression, agitation-excitement and disorganisation component. The MADRS only showed one component. A high correlation was found between the depression component of the PANSS and the overall score of the MADRS (9=0.87, P<0.001). A moderate correlation was found between the PANSS negative component and the overall score of the MADRS (p=0.51, P<0.001). Conclusions: The data suggest a five component structure of the PANSS. The depression component of the PANSS seems to be a valid way of assessing depression in patients with recent-onset schizophrenia.",

keywords = "Component structure, Montgomery Asberg Depression Rating Scale (MADRS), Positive And Negative Syndrome Scale (PANSS), Psychosis, Schizophrenia",

author = "Wolthaus, {J. E.D.} and Dingemans, {P. M.A.J.} and Schene, {A. H.} and Linszen, {D. H.} and H. Knegtering and Holthausen, {E. A.E.} and W. Cahn and R. Hijman",

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AU - Wolthaus, J. E.D.

AU - Dingemans, P. M.A.J.

AU - Schene, A. H.

AU - Linszen, D. H.

AU - Knegtering, H.

AU - Holthausen, E. A.E.

AU - Cahn, W.

AU - Hijman, R.

PY - 2000/8/2

Y1 - 2000/8/2

N2 - Rationale: Earlier studies have examined the symptom dimensions of the PANSS (Positive And Negative Syndrome Scale) in patients with chronic schizophrenia. Results have suggested that three to eight component solutions best explain underlying symptom dimensions. Objectives: To examine the component structure of the PANSS and the MADRS (Montgomery Asberg Depression Rating Scale) in young patients with recent-onset schizophrenia and related disorders and the correlations between the components of both instruments. Methods: Symptomatology was measured in 138 patients with recent-onset schizophrenia, by administering the PANSS and the MADRS. Results: Principal component analysis of the PANSS revealed five components: a positive, negative, depression, agitation-excitement and disorganisation component. The MADRS only showed one component. A high correlation was found between the depression component of the PANSS and the overall score of the MADRS (9=0.87, P<0.001). A moderate correlation was found between the PANSS negative component and the overall score of the MADRS (p=0.51, P<0.001). Conclusions: The data suggest a five component structure of the PANSS. The depression component of the PANSS seems to be a valid way of assessing depression in patients with recent-onset schizophrenia.

AB - Rationale: Earlier studies have examined the symptom dimensions of the PANSS (Positive And Negative Syndrome Scale) in patients with chronic schizophrenia. Results have suggested that three to eight component solutions best explain underlying symptom dimensions. Objectives: To examine the component structure of the PANSS and the MADRS (Montgomery Asberg Depression Rating Scale) in young patients with recent-onset schizophrenia and related disorders and the correlations between the components of both instruments. Methods: Symptomatology was measured in 138 patients with recent-onset schizophrenia, by administering the PANSS and the MADRS. Results: Principal component analysis of the PANSS revealed five components: a positive, negative, depression, agitation-excitement and disorganisation component. The MADRS only showed one component. A high correlation was found between the depression component of the PANSS and the overall score of the MADRS (9=0.87, P<0.001). A moderate correlation was found between the PANSS negative component and the overall score of the MADRS (p=0.51, P<0.001). Conclusions: The data suggest a five component structure of the PANSS. The depression component of the PANSS seems to be a valid way of assessing depression in patients with recent-onset schizophrenia.

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ER -

Component structure of the Positive And Negative Syndrome Scale (PANSS) in patients with recent-onset schizophrenia and spectrum disorders

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Keywords

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